Protein C Activity details
Description
Protein C is a natural anticoagulant protein made by the liver that helps put the brakes on excessive blood clotting, working together with Protein S to inactivate certain clotting factors once a clot has done its job. This test measures how well Protein C is functioning, and low activity — whether from an inherited deficiency or acquired causes like liver disease, vitamin K deficiency, or active blood clot formation itself — is linked to an increased risk of developing abnormal blood clots. It's typically ordered as part of a broader clotting disorder workup after an unexplained blood clot, especially in younger people or those with a family history.
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Blood tests with Protein C Activity
Explore available tests to better understand your results and gain deeper insights into your health.
Panel
Protein C Activity and Antigen
$107.99
Aids in characterization of protein C deficiency. Type I deficiency is characterized by reduction in activity (functional) and antigen levels. With type II deficiency (dysfunctional protein), antigen levels may be normal and activity levels are decreased. Acquired deficiencies may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn. Drug therapy with L-asparaginase or fluorouracil can also reduce Protein C antigen levels.
- Protein C Activity Measures the activity of Protein C, a natural anticoagulant. Low activity is linked to an increased risk of blood clots.
- Protein C Antigen Measures the actual amount of Protein C protein present, used together with the activity test to fully characterize a Protein C deficiency.
Thrombotic Risk Assessment
$3,015.99
The Thrombotic Risk Assessment assesses an individual's risk for developing a thrombotic event, such as a stroke or heart attack, by measuring factors affecting blood clotting.
- Homocysteine An amino acid byproduct of protein metabolism. Elevated levels are linked to increased cardiovascular risk and can reflect low B vitamin (B12, folate, B6) status.
- Protein C Activity Measures the activity of Protein C, a natural anticoagulant. Low activity is linked to an increased risk of blood clots.
- Activated Protein C Resistance
- Antithrombin III Activity
- Beta-2-Glycoprotein I Antibody (IgA)
- Beta-2-Glycoprotein I Antibody (IgG)
- Beta-2-Glycoprotein I Antibody (IgM)
- Cardiolipin Antibody (IgA) An antibody that attacks the body's own phospholipids (IgA type). One of the markers used to help diagnose antiphospholipid syndrome, which raises the risk of blood clots and pregnancy complications.
- Cardiolipin Antibody (IgG) An antibody that attacks the body's own phospholipids (IgG type). One of the markers used to help diagnose antiphospholipid syndrome, which raises the risk of blood clots and pregnancy complications.
- Cardiolipin Antibody (IgM) An antibody that attacks the body's own phospholipids (IgM type). One of the markers used to help diagnose antiphospholipid syndrome, which raises the risk of blood clots and pregnancy complications.
- Dilute Russell's Viper Venom Time (DRVVT) Screen
- Factor II (F2) DNA Analysis
- Lupus Anticoagulant
- Plasminogen
- Protein S Antigen, Free
- PTT-LA Screen