Protein C Activity and Antigen
Labcorp
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Labcorp
Protein C Activity and Antigen
Quest Diagnostics
Same-day appointments in most metros.
BiomarkersQuest Diagnostics biomarkers
- Protein C Activity Measures the activity of Protein C, a natural anticoagulant. Low activity is linked to an increased risk of blood clots.
- Protein C Antigen Measures the actual amount of Protein C protein present, used together with the activity test to fully characterize a Protein C deficiency.
$107.99
Description
Aids in characterization of protein C deficiency. Type I deficiency is characterized by reduction in activity (functional) and antigen levels. With type II deficiency (dysfunctional protein), antigen levels may be normal and activity levels are decreased. Acquired deficiencies may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn. Drug therapy with L-asparaginase or fluorouracil can also reduce Protein C antigen levels.
Anticoagulant interference: Expected impact by therapeutic levels (potential interference depends upondrug concentration): Vitamin K Antagonists (eg. coumadin): decrease; Heparin (UFH or LMWH): no effect to falsely increased activity levels at higher levels; Dabigatran or Argatroban (Direct Thrombin Inhibitors): may falsely increase activity; Rivaroxaban, Apixaban, Edoxaban (Factor Xa Inhibitors): may falsely increase activity.
Included biomarkers
Biomarkers
- Protein C Activity Measures the activity of Protein C, a natural anticoagulant. Low activity is linked to an increased risk of blood clots.
- Protein C Antigen Measures the actual amount of Protein C protein present, used together with the activity test to fully characterize a Protein C deficiency.
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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