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Protein C Antigen details

Description

This test measures the actual amount of Protein C protein present in your blood, as distinct from the activity test, which measures how well that Protein C is functioning. Comparing antigen (amount) and activity results helps characterize the type of Protein C deficiency present โ€” a 'type I' deficiency shows both low amount and low activity, while a 'type II' deficiency shows a normal amount of Protein C that isn't working properly, a distinction that can matter for genetic counseling and family screening.

  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Protein C Antigen

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Protein C Antigen

$245.49

This profile helps to confirm and characterize protein C deficiency.

Sample type
Plasma
Avg. sample processing time
4 Business days
Require fasting
No
Biomarkers
  • Protein C Antigen Measures the actual amount of Protein C protein present, used together with the activity test to fully characterize a Protein C deficiency.

Panel

Protein C Activity and Antigen

$107.99

Aids in characterization of protein C deficiency. Type I deficiency is characterized by reduction in activity (functional) and antigen levels. With type II deficiency (dysfunctional protein), antigen levels may be normal and activity levels are decreased. Acquired deficiencies may occur with vitamin K antagonists/deficiency, liver disease, malignancy, consumptive DIC, surgery, trauma, and hepatic immaturity of the newborn. Drug therapy with L-asparaginase or fluorouracil can also reduce Protein C antigen levels.

Sample type
Plasma
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • Protein C Activity Measures the activity of Protein C, a natural anticoagulant. Low activity is linked to an increased risk of blood clots.
  • Protein C Antigen Measures the actual amount of Protein C protein present, used together with the activity test to fully characterize a Protein C deficiency.
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