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Protein, Total and Protein Electrophoresis Blood Test

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Feature Labcorp Quest Diagnostics
Price Coming soon $23.99
Results in โ€” ~6 business days
Sample type โ€” Blood Serum
Require fasting โ€” No

About the test

Serum protein electrophoresis (SPE) is an analytical technique that provides separation of serum protein into six fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, and Gamma. Interpretation of elevation, decreased, or visual change in different fractions can be used as a diagnostic aid for a variety of different disease states and protein abnormalities, including monoclonal gammopathies (MG).

Included biomarkers & Reference ranges

Biomarker Reference range
Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues. 3.6โ€“5.1 g/dL
Alpha-1 Globulin One of the protein groups measured in a protein electrophoresis test. Changes in this fraction can be an early sign of inflammation or certain liver or lung conditions. โ€”
Alpha-2 Globulin One of the protein groups measured in a protein electrophoresis test. Elevated levels are often seen with inflammation, kidney disease (nephrotic syndrome), or certain cancers. โ€”
Beta-1 Globulin One of the protein groups measured in a protein electrophoresis test, which includes transferrin. Changes can relate to iron status or certain liver and kidney conditions. โ€”
Gamma Globulin The protein fraction that includes most of your antibodies (immunoglobulins). Elevated levels can reflect chronic infection, inflammation, or certain blood disorders. โ€”
Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status. 6.1โ€“8.1 g/dL
Abnormal Protein Band 1 Measures the amount of an unusual protein band found on serum protein electrophoresis, often a monoclonal protein that needs further testing to identify. โ€”
Abnormal Protein Band 2 Measures the amount of an unusual protein band found on serum protein electrophoresis, often a monoclonal protein that needs further testing to identify. โ€”
Abnormal Protein Band 3 Measures the amount of an unusual protein band found on serum protein electrophoresis, often a monoclonal protein that needs further testing to identify. โ€”
Beta 2 Globulin Measures the beta-2 globulin fraction on serum protein electrophoresis, a group of blood proteins that includes the immune protein complement C3. โ€”

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

Preparation

  • Overnight fasting is recommended but not required.
  • Fasting before a blood draw means you don't eat or drink anything except water.
  • Your doctor should provide any special instructions related to fasting for your test. Always follow your doctor's instructions.

How it works

  1. 1. Order online No referral or insurance
  2. 2. Get a requisition By email in 24โ€“72 hours
  3. 3. Visit a draw center Bring a matching photo ID
  4. 4. Get results Securely by email
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Consultations

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Schedule a consultation with a Hormunity specialist. Weโ€™ll walk through every marker, interpret what it means for you, and map out the next steps for your care.

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