Beta 2 Globulin details
What Beta 2 Globulin shows
Beta-2 globulin is one of the protein groups, or fractions, that serum protein electrophoresis separates your blood proteins into. This fraction contains several proteins, most notably complement C3, a part of the immune system, and sometimes some antibodies. It is measured as part of a protein electrophoresis to look at the overall pattern of your blood proteins. A higher level can be seen with inflammation, and sometimes with an abnormal protein such as a monoclonal antibody that runs in this area. A lower level can reflect low complement, for example in some immune conditions, or reduced protein production. The fraction is interpreted as part of the whole electrophoresis pattern, not alone.
Tests that include Beta 2 Globulin
Serum protein electrophoresis (SPE) is an analytical technique that provides separation of serum protein into six fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, and Gamma. Interpretation of elevation, decreased, or visual change in different fractions can be used as a diagnostic aid for a variety of different disease states and protein abnormalities, including monoclonal gammopathies (MG).
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- Alpha-1 Globulin One of the protein groups measured in a protein electrophoresis test. Changes in this fraction can be an early sign of inflammation or certain liver or lung conditions.
- Alpha-2 Globulin One of the protein groups measured in a protein electrophoresis test. Elevated levels are often seen with inflammation, kidney disease (nephrotic syndrome), or certain cancers.
- Beta-1 Globulin One of the protein groups measured in a protein electrophoresis test, which includes transferrin. Changes can relate to iron status or certain liver and kidney conditions.
- Gamma Globulin The protein fraction that includes most of your antibodies (immunoglobulins). Elevated levels can reflect chronic infection, inflammation, or certain blood disorders.
- Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status.
- Abnormal Protein Band 1 Measures the amount of an unusual protein band found on serum protein electrophoresis, often a monoclonal protein that needs further testing to identify.
- Abnormal Protein Band 2 Measures the amount of an unusual protein band found on serum protein electrophoresis, often a monoclonal protein that needs further testing to identify.
- Abnormal Protein Band 3 Measures the amount of an unusual protein band found on serum protein electrophoresis, often a monoclonal protein that needs further testing to identify.
- Beta 2 Globulin Measures the beta-2 globulin fraction on serum protein electrophoresis, a group of blood proteins that includes the immune protein complement C3.
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