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Protein Electrophoresis With Interpretation, Serum Blood Test

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Feature Labcorp Quest Diagnostics
Price $33.99 Coming soon
Results in ~4 business days โ€”
Sample type Blood Serum โ€”
Require fasting No โ€”

About the test

Serum protein electrophoresis is an analytical technique that separates serum protein into six fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, and Gamma. It is used to evaluate collagen diseases, inflammatory states, macroglobulinemia of Waldenstrom, monoclonal gammopathies, and myeloma.

Included biomarkers & Reference ranges

Biomarker Reference range
Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues. 3.6โ€“5.1 g/dL
Albumin/Globulin Ratio Compares your two main blood protein types, albumin and globulin. An abnormal ratio can point toward liver disease, kidney problems, or immune system conditions. 1โ€“2.5 Ratio
Alpha-1 Globulin One of the protein groups measured in a protein electrophoresis test. Changes in this fraction can be an early sign of inflammation or certain liver or lung conditions. โ€”
Alpha-2 Globulin One of the protein groups measured in a protein electrophoresis test. Elevated levels are often seen with inflammation, kidney disease (nephrotic syndrome), or certain cancers. โ€”
Beta-1 Globulin One of the protein groups measured in a protein electrophoresis test, which includes transferrin. Changes can relate to iron status or certain liver and kidney conditions. โ€”
Gamma Globulin The protein fraction that includes most of your antibodies (immunoglobulins). Elevated levels can reflect chronic infection, inflammation, or certain blood disorders. โ€”
Globulin A group of blood proteins that includes antibodies and various transport proteins. Assessed together with albumin to evaluate liver, kidney, and immune function. 1.9โ€“3.7 g/dL
M-Spike A distinctive spike seen on protein electrophoresis caused by an abnormal, single clone of antibody protein. Used to screen for and monitor conditions like multiple myeloma. โ€”
Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status. 6.1โ€“8.1 g/dL

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

How it works

  1. 1. Order online No referral or insurance
  2. 2. Get a requisition By email in 24โ€“72 hours
  3. 3. Visit a draw center Bring a matching photo ID
  4. 4. Get results Securely by email
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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