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Estradiol details
What Estradiol shows
Estradiol (E2) is the main and most biologically potent form of estrogen, produced primarily by the ovaries in women of reproductive age (with smaller amounts made elsewhere, including in men). It plays a central role in the menstrual cycle, fertility, bone health, and many other body systems, and levels change predictably across the menstrual cycle, pregnancy, and the transition to menopause, where they decline significantly. It's used to evaluate menstrual irregularities, fertility issues, monitor ovarian response during fertility treatments, assess menopausal status, and, in men, evaluate certain hormone imbalances or symptoms like gynecomastia.
Higher estradiol can point to hormone therapy or excess estrogen
Seen around ovulation, in pregnancy and with hormone therapy. In men, can come with breast tenderness or swelling.
Lower estradiol can point to menopause or low ovarian function
Often seen with hot flashes, missed periods, vaginal dryness or low mood.
Who might consider it:
- Irregular or missed periods, or symptoms of menopause
- Planning a pregnancy or fertility treatment
- Using estrogen or testosterone therapy and checking your dose
- Men with breast tenderness or low sex drive
What can affect your result
Cycle day
Estradiol changes through the menstrual cycle, so the same level means different things on different days.
Hormone therapy and birth control
Estrogen, testosterone and birth control change estradiol.
Biotin supplements
High doses can skew this test. Pause biotin before your draw as your lab or provider advises.
Preparation
- Fasting is not needed.
- If you have periods, test on the cycle day your provider asks for, often day 2–5 for fertility testing.
- If you use hormone therapy or birth control, tell your provider and test at the time they advise.
- Pause biotin supplements before your draw as your lab or provider advises.
Tests that include Estradiol
Estradiol (E2) is the most potent form of estrogen primarily produced by the ovaries. It plays a key role in female reproductive health, menstrual cycle regulation, and bone health, and is commonly measured to assess hormonal balance and fertility.
Biomarkers
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
Estradiol (E2) is the most potent form of estrogen primarily produced by the ovaries. It plays a key role in female reproductive health, menstrual cycle regulation, and bone health, and is commonly measured to assess hormonal balance and fertility.
Biomarkers
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
The Comprehensive Female Panel measures the levels of several hormones and other markers to provide a comprehensive assessment of a patient's health.
Biomarkers
- Glucose Your blood sugar level at the time of the test — a core marker for diagnosing and monitoring diabetes and metabolic health.
- Luteinizing Hormone (LH) A pituitary hormone that triggers ovulation in women and stimulates testosterone production in men. Used to evaluate fertility, menstrual irregularities, and reproductive hormone disorders.
- Red Blood Cell Count (RBC) Red blood cell count — the number of oxygen-carrying red blood cells in your blood, used to help diagnose anemia or polycythemia.
- HDL Cholesterol The 'good' cholesterol that helps remove excess cholesterol from your bloodstream. Higher levels are generally linked to lower cardiovascular risk.
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- Globulin A group of blood proteins that includes antibodies and various transport proteins. Assessed together with albumin to evaluate liver, kidney, and immune function.
- Sodium An essential electrolyte that regulates fluid balance, blood pressure, and nerve and muscle function.
- Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury.
- Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions.
- Total Cholesterol The combined measure of all cholesterol in your blood — HDL, LDL, and other lipoproteins together. A foundational marker of cardiovascular risk.
- Testosterone The primary male sex hormone, also present in women in smaller amounts. Evaluated for low testosterone symptoms, fertility, and reproductive hormone imbalances.
- Follicle-Stimulating Hormone (FSH) A pituitary hormone that drives egg development in women and sperm production in men. Key marker for fertility and menopause evaluation.
- Progesterone A hormone essential for the menstrual cycle and pregnancy. Used to confirm ovulation, evaluate fertility, and monitor early pregnancy.
- Albumin/Globulin Ratio Compares your two main blood protein types, albumin and globulin. An abnormal ratio can point toward liver disease, kidney problems, or immune system conditions.
- Insulin-Like Growth Factor 1 (IGF-1), LC/MS Insulin-like growth factor 1, a hormone that reflects your average growth hormone activity over time. Used to evaluate growth hormone excess or deficiency.
- Triglycerides A type of fat in your blood used for energy storage. Elevated levels are linked to increased cardiovascular risk and often reflect diet, weight, or metabolic health.
- Mean Corpuscular Hemoglobin Concentration (MCHC) Mean Corpuscular Hemoglobin Concentration — the average concentration of hemoglobin within your red blood cells, used to help classify types of anemia.
- Total Cholesterol / HDL Ratio Compares your total cholesterol to your HDL ('good') cholesterol, offering a quick snapshot of cardiovascular risk balance.
- Free Testosterone The small portion of your testosterone that's unbound and biologically active, considered a more accurate reflection of usable hormone than total testosterone.
- Mean Corpuscular Volume Mean Corpuscular Volume — the average size of your red blood cells, a key value used to help determine the cause of anemia.
- Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
- Calcium Measures the total calcium in your blood, important for bone health, muscle function, nerve signaling, and blood clotting.
- Blood Urea Nitrogen Blood urea nitrogen, a waste product filtered by your kidneys. Used along with creatinine to assess kidney function and hydration status.
- C-Reactive Protein, High Sensitivity (hs-CRP) A sensitive marker of low-grade inflammation in the body, commonly used to help assess cardiovascular disease risk.
- Hemoglobin The oxygen-carrying protein in your red blood cells. A core marker for diagnosing anemia and other blood disorders.
- Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.
- Estimated Glomerular Filtration Rate Estimated glomerular filtration rate — a calculated estimate of how well your kidneys are filtering waste from your blood, based on creatinine and other factors.
- Mean Corpuscular Hemoglobin (MCH) Mean Corpuscular Hemoglobin — the average amount of hemoglobin per red blood cell, used to help classify types of anemia.
- LDL Cholesterol, Calculated The 'bad' cholesterol that can build up in artery walls. A core marker used to assess cardiovascular disease risk.
- Carbon Dioxide Reflects the bicarbonate level in your blood, a key part of your body's acid-base balance. Abnormal levels can point to metabolic or respiratory issues.
- Non-HDL Cholesterol Total cholesterol minus HDL — capturing all the potentially artery-clogging ('bad') cholesterol particles in one number.
- Sex Hormone-Binding Globulin (SHBG) A protein that binds and transports testosterone and estrogen in your blood, determining how much hormone is 'free' and active. Important for interpreting sex hormone results.
- White Blood Cell Count (WBC) White blood cell count — the total number of white blood cells in your blood, key immune cells. Used to help detect infection, inflammation, and other blood disorders.
- T4, Free (fT4) The unbound, biologically active portion of thyroxine (T4), your main thyroid hormone. A core marker for evaluating thyroid function.
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
- Z-Score Shows how far your IGF-1 result is from the average for people of your age and sex, measured in standard deviations.
- Platelet Count Cell fragments that help your blood clot. Counted to screen for bleeding or clotting risk and various blood disorders.
- Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT.
- Mean Platelet Volume (MPV) Measures the average size of your platelets, the cells that help blood clot, and is read alongside your platelet count.
- BUN/Creatinine Ratio Compares two kidney-related waste markers to help distinguish the cause of abnormal kidney values, such as dehydration versus a kidney-specific problem.
- Dehydroepiandrosterone Sulfate (DHEA-S) The sulfated, more stable form of DHEA. A reliable marker of adrenal androgen production, used to evaluate adrenal function and androgen excess.
- Hematocrit The percentage of your blood volume made up of red blood cells. Used to help diagnose anemia or polycythemia (excess red blood cells).
- Potassium An essential electrolyte that plays a critical role in heart rhythm, muscle function, and nerve signaling.
- Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status.
- Bioavailable Testosterone The portion of your testosterone that's either free or loosely bound to albumin — the amount actually usable by your body's tissues.
- Red Cell Distribution Width (RDW) Red Cell Distribution Width — measures how much your red blood cells vary in size, helpful for narrowing down the cause of anemia.
- Chloride An electrolyte that works with sodium and potassium to maintain fluid balance and acid-base status in your body.
- Thyroid-Stimulating Hormone (TSH) A pituitary hormone that signals your thyroid to produce hormone. The primary screening test for both underactive and overactive thyroid conditions.
- Creatinine A waste product from muscle metabolism, filtered by your kidneys. One of the main markers used to assess kidney function.
- T3, Free (fT3) The unbound, biologically active portion of triiodothyronine (T3), the more potent thyroid hormone. Used to evaluate thyroid function.
This comprehensive panel evaluates key aspects of women's health, including hormone balance, thyroid function, cardiovascular health, inflammation, blood cell health, iron stores, metabolism, and liver and kidney function. It provides a broad overview of overall wellness and may help identify underlying imbalances that can affect energy, mood, metabolic health, reproductive health, and long-term health outcomes.
Biomarkers
- HDL Cholesterol The 'good' cholesterol that helps remove excess cholesterol from your bloodstream. Higher levels are generally linked to lower cardiovascular risk.
- Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT.
- Red Blood Cell Count (RBC) Red blood cell count — the number of oxygen-carrying red blood cells in your blood, used to help diagnose anemia or polycythemia.
- Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions.
- Follicle-Stimulating Hormone (FSH) A pituitary hormone that drives egg development in women and sperm production in men. Key marker for fertility and menopause evaluation.
- Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status.
- Sex Hormone-Binding Globulin (SHBG) A protein that binds and transports testosterone and estrogen in your blood, determining how much hormone is 'free' and active. Important for interpreting sex hormone results.
- Carbon Dioxide Reflects the bicarbonate level in your blood, a key part of your body's acid-base balance. Abnormal levels can point to metabolic or respiratory issues.
- Dehydroepiandrosterone Sulfate (DHEA-S) The sulfated, more stable form of DHEA. A reliable marker of adrenal androgen production, used to evaluate adrenal function and androgen excess.
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
- BUN/Creatinine Ratio Compares two kidney-related waste markers to help distinguish the cause of abnormal kidney values, such as dehydration versus a kidney-specific problem.
- Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.
- Blood Urea Nitrogen Blood urea nitrogen, a waste product filtered by your kidneys. Used along with creatinine to assess kidney function and hydration status.
- C-Reactive Protein, High Sensitivity (hs-CRP) A sensitive marker of low-grade inflammation in the body, commonly used to help assess cardiovascular disease risk.
- Albumin/Globulin Ratio Compares your two main blood protein types, albumin and globulin. An abnormal ratio can point toward liver disease, kidney problems, or immune system conditions.
- Cholesterol, Very Low Density Lipoprotein Estimates very low density lipoprotein (VLDL) cholesterol, a triglyceride-rich particle, usually calculated from triglycerides in a standard lipid panel.
- LDL Cholesterol, Calculated The 'bad' cholesterol that can build up in artery walls. A core marker used to assess cardiovascular disease risk.
- T3, Free (fT3) The unbound, biologically active portion of triiodothyronine (T3), the more potent thyroid hormone. Used to evaluate thyroid function.
- Red Cell Distribution Width (RDW) Red Cell Distribution Width — measures how much your red blood cells vary in size, helpful for narrowing down the cause of anemia.
- Free Testosterone The small portion of your testosterone that's unbound and biologically active, considered a more accurate reflection of usable hormone than total testosterone.
- Creatinine A waste product from muscle metabolism, filtered by your kidneys. One of the main markers used to assess kidney function.
- Calcium Measures the total calcium in your blood, important for bone health, muscle function, nerve signaling, and blood clotting.
- Glucose Your blood sugar level at the time of the test — a core marker for diagnosing and monitoring diabetes and metabolic health.
- Hemoglobin The oxygen-carrying protein in your red blood cells. A core marker for diagnosing anemia and other blood disorders.
- Insulin-Like Growth Factor 1 (IGF-1), LC/MS Insulin-like growth factor 1, a hormone that reflects your average growth hormone activity over time. Used to evaluate growth hormone excess or deficiency.
- White Blood Cell Count (WBC) White blood cell count — the total number of white blood cells in your blood, key immune cells. Used to help detect infection, inflammation, and other blood disorders.
- Platelet Count Cell fragments that help your blood clot. Counted to screen for bleeding or clotting risk and various blood disorders.
- Chloride An electrolyte that works with sodium and potassium to maintain fluid balance and acid-base status in your body.
- Hematocrit The percentage of your blood volume made up of red blood cells. Used to help diagnose anemia or polycythemia (excess red blood cells).
- Mean Corpuscular Volume Mean Corpuscular Volume — the average size of your red blood cells, a key value used to help determine the cause of anemia.
- Progesterone A hormone essential for the menstrual cycle and pregnancy. Used to confirm ovulation, evaluate fertility, and monitor early pregnancy.
- Thyroid-Stimulating Hormone (TSH) A pituitary hormone that signals your thyroid to produce hormone. The primary screening test for both underactive and overactive thyroid conditions.
- Luteinizing Hormone (LH) A pituitary hormone that triggers ovulation in women and stimulates testosterone production in men. Used to evaluate fertility, menstrual irregularities, and reproductive hormone disorders.
- Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
- Total Cholesterol The combined measure of all cholesterol in your blood — HDL, LDL, and other lipoproteins together. A foundational marker of cardiovascular risk.
- Triglycerides A type of fat in your blood used for energy storage. Elevated levels are linked to increased cardiovascular risk and often reflect diet, weight, or metabolic health.
- T4, Free (fT4) The unbound, biologically active portion of thyroxine (T4), your main thyroid hormone. A core marker for evaluating thyroid function.
- Estimated Glomerular Filtration Rate Estimated glomerular filtration rate — a calculated estimate of how well your kidneys are filtering waste from your blood, based on creatinine and other factors.
- Testosterone The primary male sex hormone, also present in women in smaller amounts. Evaluated for low testosterone symptoms, fertility, and reproductive hormone imbalances.
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- Mean Corpuscular Hemoglobin (MCH) Mean Corpuscular Hemoglobin — the average amount of hemoglobin per red blood cell, used to help classify types of anemia.
- Globulin A group of blood proteins that includes antibodies and various transport proteins. Assessed together with albumin to evaluate liver, kidney, and immune function.
- Potassium An essential electrolyte that plays a critical role in heart rhythm, muscle function, and nerve signaling.
- Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury.
- Mean Corpuscular Hemoglobin Concentration (MCHC) Mean Corpuscular Hemoglobin Concentration — the average concentration of hemoglobin within your red blood cells, used to help classify types of anemia.
- Sodium An essential electrolyte that regulates fluid balance, blood pressure, and nerve and muscle function.
This comprehensive panel assesses biomarkers related to hormonal health, thyroid function, metabolism, cardiovascular health, inflammation, nutrient status, and environmental exposures. The results can help provide a broader picture of overall health and support personalized wellness and treatment strategies.
Biomarkers
- Amylase An enzyme that helps digest carbohydrates, produced mainly by the pancreas and salivary glands. Elevated levels can signal pancreatitis or salivary gland problems.
- Magnesium Measures magnesium, a mineral essential for muscle, nerve, heart, and bone function.
- Testosterone The primary male sex hormone, also present in women in smaller amounts. Evaluated for low testosterone symptoms, fertility, and reproductive hormone imbalances.
- LDL Particle Number LDL particle number — counts your actual LDL ('bad' cholesterol) particles rather than just the cholesterol they carry, often a stronger cardiovascular risk indicator than standard LDL cholesterol.
- Large VLDL-P Counts the largest VLDL particles, which carry a high amount of triglycerides and are associated with greater cardiovascular risk.
- VLDL Size Measures the average size of your VLDL particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Methylmalonic Acid A compound that builds up when vitamin B12 is deficient. A more sensitive marker of B12 status than a B12 blood level alone.
- Rh Type Identifies whether your blood is Rh-positive or Rh-negative, an important factor for blood transfusions and pregnancy management.
- Homocysteine An amino acid byproduct of protein metabolism. Elevated levels are linked to increased cardiovascular risk and can reflect low B vitamin (B12, folate, B6) status.
- Uric Acid A waste product from the breakdown of purines. Elevated levels are linked to gout and kidney stones, and can also reflect metabolic health.
- HDL Size Measures the average size of your HDL ('good' cholesterol) particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Leptin A hormone released by fat cells that helps regulate appetite and energy balance. Levels generally rise with increased body fat.
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- Lipase An enzyme that helps digest fat, produced mainly by the pancreas. Elevated levels are a key marker for pancreatitis.
- Zinc Measures zinc, a trace mineral essential for immune function, wound healing, and taste/smell.
- Iron % Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.
- Unsaturated Iron Binding Capacity Unsaturated Iron-Binding Capacity — reflects how much additional iron your blood's transferrin could still carry, used with iron and TIBC to assess iron status.
- Sex Hormone-Binding Globulin (SHBG) A protein that binds and transports testosterone and estrogen in your blood, determining how much hormone is 'free' and active. Important for interpreting sex hormone results.
- Follicle-Stimulating Hormone (FSH) A pituitary hormone that drives egg development in women and sperm production in men. Key marker for fertility and menopause evaluation.
- T3, Free (fT3) The unbound, biologically active portion of triiodothyronine (T3), the more potent thyroid hormone. Used to evaluate thyroid function.
- Luteinizing Hormone (LH) A pituitary hormone that triggers ovulation in women and stimulates testosterone production in men. Used to evaluate fertility, menstrual irregularities, and reproductive hormone disorders.
- Antinuclear Antibodies Antibodies that target structures inside your own cells' nuclei. A positive result is a key screening marker for autoimmune conditions like lupus.
- Free Testosterone The small portion of your testosterone that's unbound and biologically active, considered a more accurate reflection of usable hormone than total testosterone.
- HDL Particle Number (HDL-P) HDL particle number — counts your actual HDL ('good' cholesterol) particles rather than just the cholesterol they carry, offering a more detailed cardiovascular risk picture.
- Cortisol, Total Your main stress hormone, produced by the adrenal glands. Reflects adrenal function and helps evaluate conditions like Cushing's syndrome or adrenal insufficiency.
- Thyroid-Stimulating Hormone (TSH) A pituitary hormone that signals your thyroid to produce hormone. The primary screening test for both underactive and overactive thyroid conditions.
- Mercury Measures mercury levels in your blood, used to assess exposure to this toxic heavy metal, often from certain fish or environmental sources.
- Vitamin D, 25-OH, Total The combined measure of both major forms of vitamin D (D2 and D3) in your blood — the standard test used to assess overall vitamin D status.
- Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
- HDL Large The concentration of large HDL particles in your blood, measured as part of an advanced lipid panel to add detail on cardiovascular risk.
- C-Reactive Protein, High Sensitivity (hs-CRP) A sensitive marker of low-grade inflammation in the body, commonly used to help assess cardiovascular disease risk.
- Thyroglobulin Antibodies (Anti-Tg) An autoantibody against thyroglobulin. Elevated levels are associated with autoimmune thyroid conditions like Hashimoto's thyroiditis, and checked before using thyroglobulin to monitor thyroid cancer.
- Gamma-Glutamyl Transferase (GGT) Gamma-glutamyl transferase, a liver enzyme sensitive to bile duct problems and alcohol use, often used alongside other liver tests.
- LDL Size Measures the average size of your LDL ('bad' cholesterol) particles; smaller, denser particles are considered more likely to contribute to artery plaque.
- Thyroid Peroxidase Antibodies (Anti-TPO) An autoantibody that's the most common marker of autoimmune thyroid disease, including Hashimoto's thyroiditis and Graves' disease.
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
- ABO Group Identifies your blood type (A, B, AB, or O) based on antigens on your red blood cells. Essential for safely matching blood for transfusions or transplants.
- T4, Free (fT4) The unbound, biologically active portion of thyroxine (T4), your main thyroid hormone. A core marker for evaluating thyroid function.
- Dehydroepiandrosterone Sulfate (DHEA-S) The sulfated, more stable form of DHEA. A reliable marker of adrenal androgen production, used to evaluate adrenal function and androgen excess.
- Apolipoprotein B The main protein found on LDL and other 'bad' cholesterol particles. Considered a strong indicator of cardiovascular risk, since each particle carries one ApoB molecule.
- LDL Small Measures small, dense LDL particles, a lipid subfraction associated with higher cardiovascular risk and insulin resistance.
- Prolactin A pituitary hormone best known for stimulating milk production; also checked to evaluate menstrual irregularities, fertility issues, or pituitary conditions in men and women.
- Rheumatoid Factor Measures rheumatoid factor, an autoantibody often found in rheumatoid arthritis, used with other tests to help evaluate joint pain and inflammation.
- Lead (Venous) Measures lead levels in your blood, used to assess exposure to this toxic heavy metal.
- Lipoprotein(a) A genetically-determined, LDL-like particle. Elevated levels are an independent, largely inherited risk factor for cardiovascular disease.
- Iron, Total Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
- Total Iron Binding Capacity (TIBC) Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
- LP-IR Score Lipoprotein Insulin Resistance Score — a composite score derived from lipoprotein particle measurements that estimates insulin resistance.
This comprehensive panel assesses biomarkers related to hormonal health, thyroid function, metabolism, cardiovascular health, inflammation, nutrient status, and environmental exposures. The results can help provide a broader picture of overall health and support personalized wellness and treatment strategies.
Biomarkers
- Magnesium Measures magnesium, a mineral essential for muscle, nerve, heart, and bone function.
- Testosterone The primary male sex hormone, also present in women in smaller amounts. Evaluated for low testosterone symptoms, fertility, and reproductive hormone imbalances.
- T4, Free (fT4) The unbound, biologically active portion of thyroxine (T4), your main thyroid hormone. A core marker for evaluating thyroid function.
- Prostate-Specific Antigen (PSA), % Free The percentage of your PSA that's unbound to blood proteins. A lower percentage raises suspicion for prostate cancer, helping refine an elevated total PSA result.
- Free Testosterone The small portion of your testosterone that's unbound and biologically active, considered a more accurate reflection of usable hormone than total testosterone.
- Apolipoprotein B The main protein found on LDL and other 'bad' cholesterol particles. Considered a strong indicator of cardiovascular risk, since each particle carries one ApoB molecule.
- LDL Size Measures the average size of your LDL ('bad' cholesterol) particles; smaller, denser particles are considered more likely to contribute to artery plaque.
- Homocysteine An amino acid byproduct of protein metabolism. Elevated levels are linked to increased cardiovascular risk and can reflect low B vitamin (B12, folate, B6) status.
- Antinuclear Antibodies Antibodies that target structures inside your own cells' nuclei. A positive result is a key screening marker for autoimmune conditions like lupus.
- Luteinizing Hormone (LH) A pituitary hormone that triggers ovulation in women and stimulates testosterone production in men. Used to evaluate fertility, menstrual irregularities, and reproductive hormone disorders.
- HDL Large The concentration of large HDL particles in your blood, measured as part of an advanced lipid panel to add detail on cardiovascular risk.
- Methylmalonic Acid A compound that builds up when vitamin B12 is deficient. A more sensitive marker of B12 status than a B12 blood level alone.
- Thyroid Peroxidase Antibodies (Anti-TPO) An autoantibody that's the most common marker of autoimmune thyroid disease, including Hashimoto's thyroiditis and Graves' disease.
- Rh Type Identifies whether your blood is Rh-positive or Rh-negative, an important factor for blood transfusions and pregnancy management.
- Cortisol, Total Your main stress hormone, produced by the adrenal glands. Reflects adrenal function and helps evaluate conditions like Cushing's syndrome or adrenal insufficiency.
- Follicle-Stimulating Hormone (FSH) A pituitary hormone that drives egg development in women and sperm production in men. Key marker for fertility and menopause evaluation.
- Lead (Venous) Measures lead levels in your blood, used to assess exposure to this toxic heavy metal.
- Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
- T3, Free (fT3) The unbound, biologically active portion of triiodothyronine (T3), the more potent thyroid hormone. Used to evaluate thyroid function.
- Prostate-Specific Antigen (PSA), Free The unbound portion of prostate-specific antigen. Used alongside total PSA to help assess prostate cancer risk, especially when total PSA is borderline.
- Rheumatoid Factor Measures rheumatoid factor, an autoantibody often found in rheumatoid arthritis, used with other tests to help evaluate joint pain and inflammation.
- C-Reactive Protein, High Sensitivity (hs-CRP) A sensitive marker of low-grade inflammation in the body, commonly used to help assess cardiovascular disease risk.
- Iron % Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.
- Dehydroepiandrosterone Sulfate (DHEA-S) The sulfated, more stable form of DHEA. A reliable marker of adrenal androgen production, used to evaluate adrenal function and androgen excess.
- VLDL Size Measures the average size of your VLDL particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Thyroglobulin Antibodies (Anti-Tg) An autoantibody against thyroglobulin. Elevated levels are associated with autoimmune thyroid conditions like Hashimoto's thyroiditis, and checked before using thyroglobulin to monitor thyroid cancer.
- Prostate-Specific Antigen (PSA) A protein made by the prostate gland. Used to help screen for and monitor prostate cancer, though it can also rise with benign prostate conditions.
- Uric Acid A waste product from the breakdown of purines. Elevated levels are linked to gout and kidney stones, and can also reflect metabolic health.
- Large VLDL-P Counts the largest VLDL particles, which carry a high amount of triglycerides and are associated with greater cardiovascular risk.
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- LP-IR Score Lipoprotein Insulin Resistance Score — a composite score derived from lipoprotein particle measurements that estimates insulin resistance.
- HDL Size Measures the average size of your HDL ('good' cholesterol) particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Thyroid-Stimulating Hormone (TSH) A pituitary hormone that signals your thyroid to produce hormone. The primary screening test for both underactive and overactive thyroid conditions.
- Amylase An enzyme that helps digest carbohydrates, produced mainly by the pancreas and salivary glands. Elevated levels can signal pancreatitis or salivary gland problems.
- Zinc Measures zinc, a trace mineral essential for immune function, wound healing, and taste/smell.
- Lipase An enzyme that helps digest fat, produced mainly by the pancreas. Elevated levels are a key marker for pancreatitis.
- Vitamin D, 25-OH, Total The combined measure of both major forms of vitamin D (D2 and D3) in your blood — the standard test used to assess overall vitamin D status.
- Mercury Measures mercury levels in your blood, used to assess exposure to this toxic heavy metal, often from certain fish or environmental sources.
- Iron, Total Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
- Gamma-Glutamyl Transferase (GGT) Gamma-glutamyl transferase, a liver enzyme sensitive to bile duct problems and alcohol use, often used alongside other liver tests.
- Leptin A hormone released by fat cells that helps regulate appetite and energy balance. Levels generally rise with increased body fat.
- Sex Hormone-Binding Globulin (SHBG) A protein that binds and transports testosterone and estrogen in your blood, determining how much hormone is 'free' and active. Important for interpreting sex hormone results.
- Lipoprotein(a) A genetically-determined, LDL-like particle. Elevated levels are an independent, largely inherited risk factor for cardiovascular disease.
- Prolactin A pituitary hormone best known for stimulating milk production; also checked to evaluate menstrual irregularities, fertility issues, or pituitary conditions in men and women.
- Unsaturated Iron Binding Capacity Unsaturated Iron-Binding Capacity — reflects how much additional iron your blood's transferrin could still carry, used with iron and TIBC to assess iron status.
- HDL Particle Number (HDL-P) HDL particle number — counts your actual HDL ('good' cholesterol) particles rather than just the cholesterol they carry, offering a more detailed cardiovascular risk picture.
- LDL Small Measures small, dense LDL particles, a lipid subfraction associated with higher cardiovascular risk and insulin resistance.
- ABO Group Identifies your blood type (A, B, AB, or O) based on antigens on your red blood cells. Essential for safely matching blood for transfusions or transplants.
- LDL Particle Number LDL particle number — counts your actual LDL ('bad' cholesterol) particles rather than just the cholesterol they carry, often a stronger cardiovascular risk indicator than standard LDL cholesterol.
- Total Iron Binding Capacity (TIBC) Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
This comprehensive panel assesses biomarkers related to hormonal health, thyroid function, metabolism, cardiovascular health, inflammation, nutrient status, and environmental exposures. The results can help provide a broader picture of overall health and support personalized wellness and treatment strategies.
Biomarkers
- Methylmalonic Acid A compound that builds up when vitamin B12 is deficient. A more sensitive marker of B12 status than a B12 blood level alone.
- LDL Size Measures the average size of your LDL ('bad' cholesterol) particles; smaller, denser particles are considered more likely to contribute to artery plaque.
- ABO Group Identifies your blood type (A, B, AB, or O) based on antigens on your red blood cells. Essential for safely matching blood for transfusions or transplants.
- Thyroid-Stimulating Hormone (TSH) A pituitary hormone that signals your thyroid to produce hormone. The primary screening test for both underactive and overactive thyroid conditions.
- Magnesium Measures magnesium, a mineral essential for muscle, nerve, heart, and bone function.
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- LDL Particle Number LDL particle number — counts your actual LDL ('bad' cholesterol) particles rather than just the cholesterol they carry, often a stronger cardiovascular risk indicator than standard LDL cholesterol.
- Leptin A hormone released by fat cells that helps regulate appetite and energy balance. Levels generally rise with increased body fat.
- Vitamin D, 25-OH, Total The combined measure of both major forms of vitamin D (D2 and D3) in your blood — the standard test used to assess overall vitamin D status.
- Amylase An enzyme that helps digest carbohydrates, produced mainly by the pancreas and salivary glands. Elevated levels can signal pancreatitis or salivary gland problems.
- Rheumatoid Factor Measures rheumatoid factor, an autoantibody often found in rheumatoid arthritis, used with other tests to help evaluate joint pain and inflammation.
- Uric Acid A waste product from the breakdown of purines. Elevated levels are linked to gout and kidney stones, and can also reflect metabolic health.
- Free Testosterone The small portion of your testosterone that's unbound and biologically active, considered a more accurate reflection of usable hormone than total testosterone.
- Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
- LDL Small Measures small, dense LDL particles, a lipid subfraction associated with higher cardiovascular risk and insulin resistance.
- Iron, Total Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
- Homocysteine An amino acid byproduct of protein metabolism. Elevated levels are linked to increased cardiovascular risk and can reflect low B vitamin (B12, folate, B6) status.
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
- Lipase An enzyme that helps digest fat, produced mainly by the pancreas. Elevated levels are a key marker for pancreatitis.
- Antinuclear Antibodies Antibodies that target structures inside your own cells' nuclei. A positive result is a key screening marker for autoimmune conditions like lupus.
- T4, Free (fT4) The unbound, biologically active portion of thyroxine (T4), your main thyroid hormone. A core marker for evaluating thyroid function.
- HDL Size Measures the average size of your HDL ('good' cholesterol) particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Anti-Mullerian Hormone (AMH) A hormone produced by developing egg follicles that reflects ovarian reserve — an estimate of how many eggs remain. Commonly used in fertility evaluations.
- LP-IR Score Lipoprotein Insulin Resistance Score — a composite score derived from lipoprotein particle measurements that estimates insulin resistance.
- Lead (Venous) Measures lead levels in your blood, used to assess exposure to this toxic heavy metal.
- Large VLDL-P Counts the largest VLDL particles, which carry a high amount of triglycerides and are associated with greater cardiovascular risk.
- Testosterone The primary male sex hormone, also present in women in smaller amounts. Evaluated for low testosterone symptoms, fertility, and reproductive hormone imbalances.
- Zinc Measures zinc, a trace mineral essential for immune function, wound healing, and taste/smell.
- Gamma-Glutamyl Transferase (GGT) Gamma-glutamyl transferase, a liver enzyme sensitive to bile duct problems and alcohol use, often used alongside other liver tests.
- VLDL Size Measures the average size of your VLDL particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Prolactin A pituitary hormone best known for stimulating milk production; also checked to evaluate menstrual irregularities, fertility issues, or pituitary conditions in men and women.
- C-Reactive Protein, High Sensitivity (hs-CRP) A sensitive marker of low-grade inflammation in the body, commonly used to help assess cardiovascular disease risk.
- Follicle-Stimulating Hormone (FSH) A pituitary hormone that drives egg development in women and sperm production in men. Key marker for fertility and menopause evaluation.
- Total Iron Binding Capacity (TIBC) Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
- Rh Type Identifies whether your blood is Rh-positive or Rh-negative, an important factor for blood transfusions and pregnancy management.
- Iron % Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.
- Dehydroepiandrosterone Sulfate (DHEA-S) The sulfated, more stable form of DHEA. A reliable marker of adrenal androgen production, used to evaluate adrenal function and androgen excess.
- Unsaturated Iron Binding Capacity Unsaturated Iron-Binding Capacity — reflects how much additional iron your blood's transferrin could still carry, used with iron and TIBC to assess iron status.
- Mercury Measures mercury levels in your blood, used to assess exposure to this toxic heavy metal, often from certain fish or environmental sources.
- HDL Large The concentration of large HDL particles in your blood, measured as part of an advanced lipid panel to add detail on cardiovascular risk.
- T3, Free (fT3) The unbound, biologically active portion of triiodothyronine (T3), the more potent thyroid hormone. Used to evaluate thyroid function.
- Thyroid Peroxidase Antibodies (Anti-TPO) An autoantibody that's the most common marker of autoimmune thyroid disease, including Hashimoto's thyroiditis and Graves' disease.
- Sex Hormone-Binding Globulin (SHBG) A protein that binds and transports testosterone and estrogen in your blood, determining how much hormone is 'free' and active. Important for interpreting sex hormone results.
- HDL Particle Number (HDL-P) HDL particle number — counts your actual HDL ('good' cholesterol) particles rather than just the cholesterol they carry, offering a more detailed cardiovascular risk picture.
- Cortisol, Total Your main stress hormone, produced by the adrenal glands. Reflects adrenal function and helps evaluate conditions like Cushing's syndrome or adrenal insufficiency.
- Thyroglobulin Antibodies (Anti-Tg) An autoantibody against thyroglobulin. Elevated levels are associated with autoimmune thyroid conditions like Hashimoto's thyroiditis, and checked before using thyroglobulin to monitor thyroid cancer.
- Lipoprotein(a) A genetically-determined, LDL-like particle. Elevated levels are an independent, largely inherited risk factor for cardiovascular disease.
- Apolipoprotein B The main protein found on LDL and other 'bad' cholesterol particles. Considered a strong indicator of cardiovascular risk, since each particle carries one ApoB molecule.
- Luteinizing Hormone (LH) A pituitary hormone that triggers ovulation in women and stimulates testosterone production in men. Used to evaluate fertility, menstrual irregularities, and reproductive hormone disorders.
This comprehensive panel assesses biomarkers related to hormonal health, thyroid function, metabolism, cardiovascular health, inflammation, nutrient status, and environmental exposures. The results can help provide a broader picture of overall health and support personalized wellness and treatment strategies.
Biomarkers
- Cortisol, Total Your main stress hormone, produced by the adrenal glands. Reflects adrenal function and helps evaluate conditions like Cushing's syndrome or adrenal insufficiency.
- Leptin A hormone released by fat cells that helps regulate appetite and energy balance. Levels generally rise with increased body fat.
- Total Iron Binding Capacity (TIBC) Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
- LP-IR Score Lipoprotein Insulin Resistance Score — a composite score derived from lipoprotein particle measurements that estimates insulin resistance.
- Sex Hormone-Binding Globulin (SHBG) A protein that binds and transports testosterone and estrogen in your blood, determining how much hormone is 'free' and active. Important for interpreting sex hormone results.
- Prolactin A pituitary hormone best known for stimulating milk production; also checked to evaluate menstrual irregularities, fertility issues, or pituitary conditions in men and women.
- Large VLDL-P Counts the largest VLDL particles, which carry a high amount of triglycerides and are associated with greater cardiovascular risk.
- HDL Large The concentration of large HDL particles in your blood, measured as part of an advanced lipid panel to add detail on cardiovascular risk.
- Anti-Mullerian Hormone (AMH) A hormone produced by developing egg follicles that reflects ovarian reserve — an estimate of how many eggs remain. Commonly used in fertility evaluations.
- Magnesium Measures magnesium, a mineral essential for muscle, nerve, heart, and bone function.
- T3, Free (fT3) The unbound, biologically active portion of triiodothyronine (T3), the more potent thyroid hormone. Used to evaluate thyroid function.
- Iron, Total Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
- Vitamin D, 25-OH, Total The combined measure of both major forms of vitamin D (D2 and D3) in your blood — the standard test used to assess overall vitamin D status.
- Antinuclear Antibodies Antibodies that target structures inside your own cells' nuclei. A positive result is a key screening marker for autoimmune conditions like lupus.
- LDL Size Measures the average size of your LDL ('bad' cholesterol) particles; smaller, denser particles are considered more likely to contribute to artery plaque.
- Thyroglobulin Antibodies (Anti-Tg) An autoantibody against thyroglobulin. Elevated levels are associated with autoimmune thyroid conditions like Hashimoto's thyroiditis, and checked before using thyroglobulin to monitor thyroid cancer.
- Iron % Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.
- Lead (Venous) Measures lead levels in your blood, used to assess exposure to this toxic heavy metal.
- Mercury Measures mercury levels in your blood, used to assess exposure to this toxic heavy metal, often from certain fish or environmental sources.
- HDL Particle Number (HDL-P) HDL particle number — counts your actual HDL ('good' cholesterol) particles rather than just the cholesterol they carry, offering a more detailed cardiovascular risk picture.
- Apolipoprotein B The main protein found on LDL and other 'bad' cholesterol particles. Considered a strong indicator of cardiovascular risk, since each particle carries one ApoB molecule.
- Methylmalonic Acid A compound that builds up when vitamin B12 is deficient. A more sensitive marker of B12 status than a B12 blood level alone.
- Dehydroepiandrosterone Sulfate (DHEA-S) The sulfated, more stable form of DHEA. A reliable marker of adrenal androgen production, used to evaluate adrenal function and androgen excess.
- T4, Free (fT4) The unbound, biologically active portion of thyroxine (T4), your main thyroid hormone. A core marker for evaluating thyroid function.
- Uric Acid A waste product from the breakdown of purines. Elevated levels are linked to gout and kidney stones, and can also reflect metabolic health.
- Prostate-Specific Antigen (PSA), % Free The percentage of your PSA that's unbound to blood proteins. A lower percentage raises suspicion for prostate cancer, helping refine an elevated total PSA result.
- Luteinizing Hormone (LH) A pituitary hormone that triggers ovulation in women and stimulates testosterone production in men. Used to evaluate fertility, menstrual irregularities, and reproductive hormone disorders.
- Free Testosterone The small portion of your testosterone that's unbound and biologically active, considered a more accurate reflection of usable hormone than total testosterone.
- Homocysteine An amino acid byproduct of protein metabolism. Elevated levels are linked to increased cardiovascular risk and can reflect low B vitamin (B12, folate, B6) status.
- Unsaturated Iron Binding Capacity Unsaturated Iron-Binding Capacity — reflects how much additional iron your blood's transferrin could still carry, used with iron and TIBC to assess iron status.
- C-Reactive Protein, High Sensitivity (hs-CRP) A sensitive marker of low-grade inflammation in the body, commonly used to help assess cardiovascular disease risk.
- Gamma-Glutamyl Transferase (GGT) Gamma-glutamyl transferase, a liver enzyme sensitive to bile duct problems and alcohol use, often used alongside other liver tests.
- Lipase An enzyme that helps digest fat, produced mainly by the pancreas. Elevated levels are a key marker for pancreatitis.
- Thyroid Peroxidase Antibodies (Anti-TPO) An autoantibody that's the most common marker of autoimmune thyroid disease, including Hashimoto's thyroiditis and Graves' disease.
- Prostate-Specific Antigen (PSA) A protein made by the prostate gland. Used to help screen for and monitor prostate cancer, though it can also rise with benign prostate conditions.
- LDL Small Measures small, dense LDL particles, a lipid subfraction associated with higher cardiovascular risk and insulin resistance.
- Testosterone The primary male sex hormone, also present in women in smaller amounts. Evaluated for low testosterone symptoms, fertility, and reproductive hormone imbalances.
- Zinc Measures zinc, a trace mineral essential for immune function, wound healing, and taste/smell.
- ABO Group Identifies your blood type (A, B, AB, or O) based on antigens on your red blood cells. Essential for safely matching blood for transfusions or transplants.
- Follicle-Stimulating Hormone (FSH) A pituitary hormone that drives egg development in women and sperm production in men. Key marker for fertility and menopause evaluation.
- Amylase An enzyme that helps digest carbohydrates, produced mainly by the pancreas and salivary glands. Elevated levels can signal pancreatitis or salivary gland problems.
- Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
- Prostate-Specific Antigen (PSA), Free The unbound portion of prostate-specific antigen. Used alongside total PSA to help assess prostate cancer risk, especially when total PSA is borderline.
- HDL Size Measures the average size of your HDL ('good' cholesterol) particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
- VLDL Size Measures the average size of your VLDL particles, used alongside particle number for a more detailed cardiovascular risk assessment.
- Lipoprotein(a) A genetically-determined, LDL-like particle. Elevated levels are an independent, largely inherited risk factor for cardiovascular disease.
- LDL Particle Number LDL particle number — counts your actual LDL ('bad' cholesterol) particles rather than just the cholesterol they carry, often a stronger cardiovascular risk indicator than standard LDL cholesterol.
- Estradiol The main and most potent form of estrogen. Key for reproductive health in women and also present in men; used to evaluate menstrual, fertility, and hormone-related concerns.
- Thyroid-Stimulating Hormone (TSH) A pituitary hormone that signals your thyroid to produce hormone. The primary screening test for both underactive and overactive thyroid conditions.
- Rheumatoid Factor Measures rheumatoid factor, an autoantibody often found in rheumatoid arthritis, used with other tests to help evaluate joint pain and inflammation.
- Rh Type Identifies whether your blood is Rh-positive or Rh-negative, an important factor for blood transfusions and pregnancy management.
ConsultationsConsultation
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