Double-Stranded DNA (dsDNA) Antibody details
What Double-Stranded DNA (dsDNA) Antibody shows
Anti-double-stranded DNA (anti-dsDNA) antibodies are autoantibodies that specifically target your own DNA, and they're highly specific for lupus — meaning a positive result strongly supports the diagnosis, especially when combined with a positive ANA and suggestive symptoms. Anti-dsDNA levels often rise and fall with lupus disease activity, particularly correlating with kidney involvement (lupus nephritis), which makes this test useful not just for diagnosis but for monitoring flares and treatment response over time in someone already diagnosed.
Tests that include Double-Stranded DNA (dsDNA) Antibody
This test measures anti-double-stranded DNA (anti-dsDNA) antibodies. It is used to confirm a diagnosis of systemic lupus erythematosus (SLE).
- Double-Stranded DNA (dsDNA) Antibody Antibodies against double-stranded DNA. Highly specific for lupus and often used to track disease activity.
This test measures anti-double-stranded DNA (anti-dsDNA) antibodies. It is used to confirm a diagnosis of systemic lupus erythematosus (SLE).
- Double-Stranded DNA (dsDNA) Antibody Antibodies against double-stranded DNA. Highly specific for lupus and often used to track disease activity.
ANA + 11 Components is a comprehensive blood test that includes the presence of antinuclear antibodies (ANAs), which are autoantibodies targeting the cell nucleus. A positive ANA screen suggests potential autoimmune activity. 11 ANA Components tests for 11 specific autoantibodies against distinct nuclear antigens, helping to identify or differentiate particular autoimmune diseases.
- Chromatin Antibodies Autoantibodies that target chromatin (DNA-protein complexes) inside your cells. Associated with lupus and other autoimmune conditions.
- Anti-Jo-1 An autoantibody associated with certain autoimmune muscle and lung conditions, including polymyositis, dermatomyositis, and antisynthetase syndrome.
- Ribosomal P Antibody An autoantibody associated with lupus, particularly linked to neuropsychiatric symptoms in some patients.
- RNP Antibody An autoantibody associated with mixed connective tissue disease and, at times, lupus.
- Smith (Sm) Antibody An autoantibody highly specific for lupus, though present in only a portion of people with the disease.
- Centromere B Antibody Autoantibodies that target a structure inside your cells called the centromere. Strongly associated with limited scleroderma (CREST syndrome).
- Double-Stranded DNA (dsDNA) Antibody Antibodies against double-stranded DNA. Highly specific for lupus and often used to track disease activity.
- Scleroderma (Scl-70) Antibody An autoantibody strongly associated with diffuse systemic sclerosis (scleroderma), a more widespread form of the disease.
- Sjögren's Syndrome A (SS-A/Ro) Antibody An autoantibody associated with Sjögren's syndrome and lupus; also relevant in pregnancy due to a risk of neonatal heart complications.
- Sjögren's Syndrome B (SS-B/La) Antibody An autoantibody associated with Sjögren's syndrome and lupus, often found alongside SS-A antibodies.
- Sm/RNP Antibody Measures antibodies to the Sm/RNP complex, autoantibodies linked to mixed connective tissue disease and lupus, used when evaluating a positive ANA.
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