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Tissue Transglutaminase IgA details

Description

Tissue transglutaminase (tTG) IgA is the primary, first-line antibody test used to screen for celiac disease, an autoimmune reaction to gluten that damages the lining of the small intestine. It's highly sensitive and specific for celiac disease in people with normal IgA levels, and a significantly elevated result, especially combined with typical symptoms (digestive issues, fatigue, or nutrient deficiencies), strongly supports the diagnosis, which is generally then confirmed with a small intestine biopsy. Accurate results depend on continuing to eat gluten leading up to testing, since a gluten-free diet can cause antibody levels to normalize even if celiac disease is present.

  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Tissue Transglutaminase IgA

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Tissue Transglutaminase IgA

$52.49

This test measures IgA antibodies to tissue transglutaminase. It is used to aid in the diagnosis of gluten-sensitive enteropathies such as celiac disease.

Sample type
Serum
Avg. sample processing time
3 Business days
Require fasting
No
Biomarkers
  • Tissue Transglutaminase IgA The primary antibody test used to screen for celiac disease.

Panel

Celiac Disease Diagnostic Panel

$90.49

Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.

Sample type
Serum
Avg. sample processing time
4 Business days
Require fasting
No
Biomarkers

Celiac Disease Evaluation

$151.49

This test provides a comprehensive evaluation of the antibodies that are characteristic of celiac disease. Celiac disease is also associated with selective IgA deficiency and autoimmune disorders.

Sample type
Serum
Avg. sample processing time
3 Business days
Require fasting
No
Biomarkers

Tissue Transglutaminase (tTG) Antibodies (IgG, IgA)

$45.49

This test is crucial for diagnosing conditions related to gluten sensitivity, such as Celiac Sprue Disease and dermatitis herpetiformis, a skin condition. It checks for specific antibodies (IgA and IgG) in your blood. The IgA test is standard for diagnosing these conditions, but if you're IgA-deficient, the IgG test can be used instead. The IgG test can also help identify gluten-sensitive enteropathies beyond what the IgA test can find.

Sample type
Serum
Avg. sample processing time
4 Business days
Require fasting
No
Biomarkers
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