Immunoglobulin A (IgA) details
What Immunoglobulin A (IgA) shows
Immunoglobulin A (IgA) is one of your body's main antibody classes, concentrated especially in mucous membranes — the lining of your gut, respiratory tract, and other surfaces exposed to the outside world — where it serves as a first line of immune defense. Low IgA is one of the most common inherited immune deficiencies, and while many people with it have no symptoms, some experience recurrent infections or increased risk of certain autoimmune conditions. Total IgA is also routinely checked before celiac disease antibody testing (like tTG-IgA), since IgA deficiency can cause those tests to give a false-negative result.
Tests that include Immunoglobulin A (IgA)
Immunoglobulin A (IgA Total) is an antibody primarily found in mucous membranes like the respiratory and gastrointestinal tracts. It plays a key role in mucosal immunity, and measuring total IgA helps assess immune function and diagnose certain immunodeficiencies or chronic infections.
- Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.
Immunoglobulin A (IgA Total) is an antibody primarily found in mucous membranes like the respiratory and gastrointestinal tracts. It plays a key role in mucosal immunity, and measuring total IgA helps assess immune function and diagnose certain immunodeficiencies or chronic infections.
- Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.
Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.
- Tissue Transglutaminase IgA The primary antibody test used to screen for celiac disease.
- Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.
- Gliadin (Deamidated) Antibody (IgA) Measures IgA antibodies to deamidated gliadin, a gluten fragment, used to help evaluate celiac disease alongside other celiac tests.
- Gliadin (Deamidated) Antibody (IgG) Measures IgG antibodies to deamidated gliadin, a gluten fragment, used to help evaluate celiac disease, especially when IgA is low.
- Tissue Transglutaminase (tTG) Antibody (IgG) An antibody used to screen for celiac disease, particularly useful in people with IgA deficiency.
This test measures total IgG, IgA, and IgM. Elevated IgG, IgA, and/or IgM levels are seen in hypergammaglobulinemia, chronic inflammatory conditions, and lymphoproliferative diseases. Decreased levels are associated with hypogammaglobulinemia and immunodeficiency states.
- Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.
- Immunoglobulin G (IgG) Your most abundant antibody class, providing long-term immune memory against past infections. Low levels can point to an immune deficiency.
- Immunoglobulin M (IgM) The antibody class your body produces first in response to a new infection. Elevated levels often indicate a recent or acute infection.
This test measures total IgG, IgA, and IgM. Elevated IgG, IgA, and/or IgM levels are seen in hypergammaglobulinemia, chronic inflammatory conditions, and lymphoproliferative diseases. Decreased levels are associated with hypogammaglobulinemia and immunodeficiency states.
- Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.
- Immunoglobulin G (IgG) Your most abundant antibody class, providing long-term immune memory against past infections. Low levels can point to an immune deficiency.
- Immunoglobulin M (IgM) The antibody class your body produces first in response to a new infection. Elevated levels often indicate a recent or acute infection.
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