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Immunoglobulin A (IgA) details

Description

Immunoglobulin A (IgA) is one of your body's main antibody classes, concentrated especially in mucous membranes โ€” the lining of your gut, respiratory tract, and other surfaces exposed to the outside world โ€” where it serves as a first line of immune defense. Low IgA is one of the most common inherited immune deficiencies, and while many people with it have no symptoms, some experience recurrent infections or increased risk of certain autoimmune conditions. Total IgA is also routinely checked before celiac disease antibody testing (like tTG-IgA), since IgA deficiency can cause those tests to give a false-negative result.

  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Immunoglobulin A (IgA)

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Immunoglobulin A

$12.49

Immunoglobulin A (IgA Total) is an antibody primarily found in mucous membranes like the respiratory and gastrointestinal tracts. It plays a key role in mucosal immunity, and measuring total IgA helps assess immune function and diagnose certain immunodeficiencies or chronic infections.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.

Panel

Celiac Disease Diagnostic Panel

$90.49

Celiac disease is characterized by the presence of Transglutaminase, Gliadin, and Reticulin Antibodies. Such patients display a hypersensitivity to gluten (wheat) in their diet. The antibody is undetectable when patients with hypersensitivity are placed on gluten-free diets. Antibody IgA is more specific and IgG is more sensitive to Celiac disease.

Sample type
Serum
Avg. sample processing time
4 Business days
Require fasting
No
Biomarkers

Immunoglobulins A/G/M

$35.99

This test measures total IgG, IgA, and IgM. Elevated IgG, IgA, and/or IgM levels are seen in hypergammaglobulinemia, chronic inflammatory conditions, and lymphoproliferative diseases. Decreased levels are associated with hypogammaglobulinemia and immunodeficiency states.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Immunoglobulin A (IgA) One of your main antibody classes, concentrated in mucous membranes (gut, respiratory tract). Low levels are linked to recurrent infections; also checked before certain other antibody tests, like celiac panels.
  • Immunoglobulin G (IgG) Your most abundant antibody class, providing long-term immune memory against past infections. Low levels can point to an immune deficiency.
  • Immunoglobulin M (IgM) The antibody class your body produces first in response to a new infection. Elevated levels often indicate a recent or acute infection.
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