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Hepatic Function Panel with Globulin and Indirect Bilirubin Blood Test

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Feature Labcorp Quest Diagnostics
Price Coming soon $6.99
Results in โ€” ~5 business days
Sample type โ€” Blood Serum
Require fasting โ€” No

About the test

This test is crucial for assessing liver injury, diagnosing liver diseases, and monitoring the treatment of liver diseases as well as the adverse effects of drugs that may harm the liver. It checks for levels of total protein, albumin, globulin, albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).

ALT, AST, ALP, and bilirubin levels can indicate liver injury. ALT is more specific to the liver compared to AST. High levels of ALT and AST suggest liver cell injury, while high ALP and bilirubin levels suggest bile duct issues. High direct bilirubin levels can point to liver or bile duct problems. Albumin levels can show how well the liver is making proteins, which is a sign of its overall health.

This test is especially useful for people taking medications that might harm the liver, those with viral hepatitis, signs of chronic liver disease, risk factors for liver disease, or a family history of liver issues.

Understanding the results of each component can help in diagnosing specific liver conditions. Sometimes, further tests may be needed to clarify the results.

It's important to remember that liver enzymes show liver injury, not how well the liver is functioning. Tests like bilirubin, albumin, and prothrombin time can give a better picture of the liver's health.

Results should be viewed in the context of your overall health and history.

Included biomarkers & Reference ranges

Biomarker Reference range
Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions. 35โ€“150 IU/L
Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury. 6โ€“29 IU/L
Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT. 10โ€“35 IU/L
Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues. 3.6โ€“5.1 g/dL
Albumin/Globulin Ratio Compares your two main blood protein types, albumin and globulin. An abnormal ratio can point toward liver disease, kidney problems, or immune system conditions. 1โ€“2.5 Ratio
Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown. 0โ€“0.2 mg/L
Globulin A group of blood proteins that includes antibodies and various transport proteins. Assessed together with albumin to evaluate liver, kidney, and immune function. 1.9โ€“3.7 g/dL
Indirect Bilirubin The form of bilirubin not yet processed by your liver, produced from the normal breakdown of red blood cells. Elevated levels can point to increased red blood cell breakdown or a liver processing problem. 0.2โ€“1.2 mg/dL
Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice. 0.2โ€“1.2 mg/dL
Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status. 6.1โ€“8.1 g/dL

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

How it works

  1. 1. Order online No referral or insurance
  2. 2. Get a requisition By email in 24โ€“72 hours
  3. 3. Visit a draw center Bring a matching photo ID
  4. 4. Get results Securely by email
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Consultations

Not sure how to read your results? We can help.

Schedule a consultation with a Hormunity specialist. Weโ€™ll walk through every marker, interpret what it means for you, and map out the next steps for your care.

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