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Direct Bilirubin details

Description

Direct (conjugated) bilirubin is the form of bilirubin that your liver has already chemically processed, making it water-soluble so it can be excreted into bile and eventually leave the body through your digestive tract. An elevated direct bilirubin specifically points toward a problem after the liver has done its initial processing — either impaired excretion by the liver cells themselves or a blockage somewhere in the bile ducts (such as gallstones or a tumor), which causes it to back up into the bloodstream. This distinguishes it from elevated indirect bilirubin, which more often points toward increased red blood cell breakdown occurring before the liver even gets involved.

Optimal & Reference range

Direct Bilirubin

mg/L
  • Below optimal
  • Optimal
  • Above optimal
  • High
Optimal range
0.1 - 0.15
Reference range
0 - 0.2
Out of range
>0.2

Your Direct Bilirubin result

Enter your value to see how it compares to the original range.

Interpretation

  • Below optimal: Your result is within the reference range, but below the range we consider optimal.
  • Optimal: Your result is within the optimal range.
  • Above optimal: Your result is within the reference range, but above the range we consider optimal.
  • High: Your result is above the reference range. Discuss it with your healthcare provider, who can interpret it alongside your symptoms and other results.
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Direct Bilirubin

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Direct Bilirubin

 $5.99

Bilirubin, Direct (also called conjugated bilirubin) is a form of bilirubin that has been processed by the liver and made water-soluble for excretion into bile.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown.

Panel

Bilirubin, Total and Direct

 $9.49

This panel measures total, direct, and indirect bilirubin. It is used to evaluate liver and biliary diseases.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown.
  • Indirect Bilirubin The form of bilirubin not yet processed by your liver, produced from the normal breakdown of red blood cells. Elevated levels can point to increased red blood cell breakdown or a liver processing problem.
  • Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.

Hepatic Function Panel

 $7.99

The Hepatic Function Panel analyzes a variety of important liver health markers to investigate overall hepatic function.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions.
  • Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury.
  • Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT.
  • Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
  • Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown.
  • Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.
  • Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status.

Hepatic Function Panel, Plasma

 $9.99

This test is crucial for assessing liver injury, diagnosing liver diseases, and monitoring the treatment of liver conditions or the adverse effects of drugs that may harm the liver. It measures various components such as total protein, albumin, globulin, albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).

Sample type
Plasma
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions.
  • Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury.
  • Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT.
  • Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
  • Albumin/Globulin Ratio Compares your two main blood protein types, albumin and globulin. An abnormal ratio can point toward liver disease, kidney problems, or immune system conditions.
  • Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown.
  • Globulin A group of blood proteins that includes antibodies and various transport proteins. Assessed together with albumin to evaluate liver, kidney, and immune function.
  • Indirect Bilirubin The form of bilirubin not yet processed by your liver, produced from the normal breakdown of red blood cells. Elevated levels can point to increased red blood cell breakdown or a liver processing problem.
  • Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.
  • Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status.

Hepatic Function Panel with Globulin and Indirect Bilirubin

 $6.99

This test is crucial for assessing liver injury, diagnosing liver diseases, and monitoring the treatment of liver diseases as well as the adverse effects of drugs that may harm the liver. It checks for levels of total protein, albumin, globulin, albumin/globulin ratio, total bilirubin, direct bilirubin, indirect bilirubin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).

Sample type
Serum
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions.
  • Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury.
  • Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT.
  • Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
  • Albumin/Globulin Ratio Compares your two main blood protein types, albumin and globulin. An abnormal ratio can point toward liver disease, kidney problems, or immune system conditions.
  • Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown.
  • Globulin A group of blood proteins that includes antibodies and various transport proteins. Assessed together with albumin to evaluate liver, kidney, and immune function.
  • Indirect Bilirubin The form of bilirubin not yet processed by your liver, produced from the normal breakdown of red blood cells. Elevated levels can point to increased red blood cell breakdown or a liver processing problem.
  • Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.
  • Total Protein The combined amount of all proteins in your blood, mainly albumin and globulins, used to help evaluate liver, kidney, and nutritional status.

Hepatic Function Panel without Total Protein

 $9.49

This panel is designed to help in assessing liver damage, diagnosing liver conditions, and monitoring the treatment of liver diseases as well as the side effects of drugs that may harm the liver. This test checks levels of albumin, total bilirubin, direct bilirubin, indirect bilirubin (calculated), alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT).

Sample type
Serum
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • Alkaline Phosphatase (ALP) An enzyme found mainly in the liver and bones. High levels can signal liver disease, bile duct blockage, or bone conditions.
  • Alanine Aminotransferase (ALT) A liver enzyme released into the blood when liver cells are damaged. One of the main markers used to screen for liver inflammation or injury.
  • Aspartate Aminotransferase (AST) An enzyme found in the liver, heart, and muscles. Elevated levels can point to liver damage, though it's less liver-specific than ALT.
  • Albumin The main protein made by your liver, which helps balance fluids and carries hormones, vitamins, and medications through your blood. Low levels can point to liver, kidney, or nutrition issues.
  • Direct Bilirubin The form of bilirubin already processed by your liver. Elevated levels point toward a liver or bile-duct problem rather than red blood cell breakdown.
  • Indirect Bilirubin The form of bilirubin not yet processed by your liver, produced from the normal breakdown of red blood cells. Elevated levels can point to increased red blood cell breakdown or a liver processing problem.
  • Total Bilirubin The combined level of both processed and unprocessed bilirubin in your blood, a byproduct of red blood cell breakdown. Used to evaluate liver function and jaundice.
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