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Vitamin B12 details

Description

Vitamin B12 (cobalamin) is essential for red blood cell production, nerve function, and DNA synthesis, and — unlike most other vitamins — it's found almost exclusively in animal-based foods, meaning vegans, vegetarians, older adults (who absorb it less efficiently), and people with certain digestive conditions (like pernicious anemia or after gastric surgery) are at higher risk of deficiency. Low B12 can cause fatigue, weakness, numbness or tingling in the hands and feet, memory or mood changes, and a specific type of anemia (megaloblastic anemia). Because deficiency can sometimes be masked or complicated by folate status, and because a B12 level alone can occasionally be misleading, methylmalonic acid is sometimes checked as a more sensitive follow-up test.

Optimal & Reference range

Vitamin B12

pg/mL
  • Low
  • Below optimal
  • Optimal
  • High
Optimal range
545 - 1100
Reference range
200 - 1100
Out of range
<200 or >1100

Your Vitamin B12 result

Enter your value to see how it compares to the original range.

Interpretation

  • Low: Your result is below the reference range. Discuss it with your healthcare provider, who can interpret it alongside your symptoms and other results.
  • Below optimal: Your result is within the reference range, but below the range we consider optimal.
  • Optimal: Your result is within the optimal range.
  • High: Your result is above the reference range. Discuss it with your healthcare provider, who can interpret it alongside your symptoms and other results.
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Vitamin B12

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Vitamin B12

 $15.49

Vitamin B12 is a water-soluble vitamin essential for red blood cell production, neurological function, and DNA synthesis. It is commonly assessed to investigate fatigue, neuropathy, cognitive issues, or megaloblastic anemia.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.

Vitamin B12 (Cobalamin)

 $6.99

This test measures the level of Vitamin B12 in the body, which is crucial for nerve health and the production of DNA and red blood cells. Low levels of Vitamin B12 can indicate conditions such as pernicious anemia, issues from stomach surgery (total or partial gastrectomy), problems with absorbing nutrients (malabsorption), and certain inherited disorders.

Sample type
Serum
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.

Panel

Anemia Profile B

 $83.00

This panel checks key markers to see if the patient has levels that point towards anemia.

Sample type
Serum Whole Blood
Avg. sample processing time
6 Business days
Require fasting
No
Biomarkers
  • RDW Red Cell Distribution Width — measures how much your red blood cells vary in size, helpful for narrowing down the cause of anemia.
  • MCV Mean Corpuscular Volume — the average size of your red blood cells, a key value used to help determine the cause of anemia.
  • Reticulocyte Count The number of young red blood cells in your blood, reflecting how actively your bone marrow is producing new cells.
  • Eosinophils (%) The percentage of your white blood cells that are eosinophils, elevated with allergies, asthma, or parasitic infections.
  • Hematocrit The percentage of your blood volume made up of red blood cells. Used to help diagnose anemia or polycythemia (excess red blood cells).
  • MCH Mean Corpuscular Hemoglobin — the average amount of hemoglobin per red blood cell, used to help classify types of anemia.
  • Hemoglobin The oxygen-carrying protein in your red blood cells. A core marker for diagnosing anemia and other blood disorders.
  • Neutrophil Count The number of neutrophils, the most abundant white blood cell type and a first-line defense against infection, in your blood.
  • Platelets Cell fragments that help your blood clot. Counted to screen for bleeding or clotting risk and various blood disorders.
  • Iron Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
  • Basophil Count The number of basophils, a type of white blood cell involved in allergic and inflammatory responses, in your blood.
  • Monocytes (%) The percentage of your white blood cells that are monocytes, cells that help fight infection and clear damaged tissue.
  • Eosinophil Count The number of eosinophils, a white blood cell type involved in allergic reactions and parasite defense, in your blood.
  • RBC Red blood cell count — the number of oxygen-carrying red blood cells in your blood, used to help diagnose anemia or polycythemia.
  • Basophils (%) The percentage of your white blood cells that are basophils, a cell type involved in allergic and inflammatory responses.
  • WBC White blood cell count — the total number of white blood cells in your blood, key immune cells. Used to help detect infection, inflammation, and other blood disorders.
  • UIBC Unsaturated Iron-Binding Capacity — reflects how much additional iron your blood's transferrin could still carry, used with iron and TIBC to assess iron status.
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.
  • Neutrophils (%) The percentage of your white blood cells that are neutrophils, a first-line defense against infection.
  • TIBC Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
  • Folate Vitamin B9, needed for cell division, DNA synthesis, and red blood cell production. Low levels can cause a type of anemia and are important in pregnancy.
  • Lymphocytes (%) The percentage of your white blood cells that are lymphocytes, key immune cells including T-cells, B-cells, and NK cells.
  • Monocyte Count The number of monocytes, white blood cells that help fight infection and clear damaged cells, in your blood.
  • Lymphocyte Count The number of lymphocytes, white blood cells central to your immune response (including T-cells, B-cells, and NK cells), in your blood.
  • Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
  • MCHC Mean Corpuscular Hemoglobin Concentration — the average concentration of hemoglobin within your red blood cells, used to help classify types of anemia.
  • Transferrin Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.

Anemia Profile B with Full Differential

 $46.49

This panel checks key markers to determine if the patient has levels that point towards anemia.

Sample type
Serum Whole Blood
Avg. sample processing time
5 Business days
Require fasting
Yes
Biomarkers
  • Myelocytes (%)
  • Neutrophils (%) The percentage of your white blood cells that are neutrophils, a first-line defense against infection.
  • Hemoglobin The oxygen-carrying protein in your red blood cells. A core marker for diagnosing anemia and other blood disorders.
  • Mean Corpuscular Volume Mean Corpuscular Volume — the average size of your red blood cells, a key value used to help determine the cause of anemia.
  • Reticulocyte Count, Automated
  • Nucleated RBC
  • Lymphocytes The number of lymphocytes, white blood cells central to your immune response (including T-cells, B-cells, and NK cells), in your blood.
  • Monocytes The number of monocytes, white blood cells that help fight infection and clear damaged cells, in your blood.
  • Red Cell Distribution Width (RDW) Red Cell Distribution Width — measures how much your red blood cells vary in size, helpful for narrowing down the cause of anemia.
  • Mean Corpuscular Hemoglobin (MCH) Mean Corpuscular Hemoglobin — the average amount of hemoglobin per red blood cell, used to help classify types of anemia.
  • Folate Vitamin B9, needed for cell division, DNA synthesis, and red blood cell production. Low levels can cause a type of anemia and are important in pregnancy.
  • Iron % Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.
  • Mean Corpuscular Hemoglobin Concentration (MCHC) Mean Corpuscular Hemoglobin Concentration — the average concentration of hemoglobin within your red blood cells, used to help classify types of anemia.
  • Promyelocytes
  • Blasts (%)
  • Red Blood Cell Count (RBC) Red blood cell count — the number of oxygen-carrying red blood cells in your blood, used to help diagnose anemia or polycythemia.
  • Lymphocytes (%) The percentage of your white blood cells that are lymphocytes, key immune cells including T-cells, B-cells, and NK cells.
  • Promyelocytes (%)
  • Eosinophils The number of eosinophils, a white blood cell type involved in allergic reactions and parasite defense, in your blood.
  • Band Neutrophils (%)
  • Nucleated RBC (%)
  • Reticulocyte, Absolute
  • Band Neutrophils
  • Mean Platelet Volume (MPV)
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.
  • Myelocytes
  • Metamyelocytes
  • Hematocrit The percentage of your blood volume made up of red blood cells. Used to help diagnose anemia or polycythemia (excess red blood cells).
  • Total Iron Binding Capacity (TIBC) Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
  • Blasts
  • Monocytes (%) The percentage of your white blood cells that are monocytes, cells that help fight infection and clear damaged tissue.
  • White Blood Cell Count (WBC) White blood cell count — the total number of white blood cells in your blood, key immune cells. Used to help detect infection, inflammation, and other blood disorders.
  • Basophils The number of basophils, a type of white blood cell involved in allergic and inflammatory responses, in your blood.
  • Eosinophils (%) The percentage of your white blood cells that are eosinophils, elevated with allergies, asthma, or parasitic infections.
  • Metamyelocytes (%)
  • Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
  • Reactive Lymphocytes
  • Basophils (%) The percentage of your white blood cells that are basophils, a cell type involved in allergic and inflammatory responses.
  • Platelet Count Cell fragments that help your blood clot. Counted to screen for bleeding or clotting risk and various blood disorders.
  • Iron, Total Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
  • Neutrophils The number of neutrophils, the most abundant white blood cell type and a first-line defense against infection, in your blood.

Anemia Profile B with UIBC

 $74.49

This panel evaluates red blood cells, iron status, and other blood markers that are important for identifying and monitoring anemia.

Sample type
Serum Whole Blood
Avg. sample processing time
6 Business days
Require fasting
No
Biomarkers
  • Basophils (%) The percentage of your white blood cells that are basophils, a cell type involved in allergic and inflammatory responses.
  • Basophils The number of basophils, a type of white blood cell involved in allergic and inflammatory responses, in your blood.
  • Reticulocyte Count, Automated
  • Unsaturated Iron Binding Capacity
  • Red Cell Distribution Width (RDW) Red Cell Distribution Width — measures how much your red blood cells vary in size, helpful for narrowing down the cause of anemia.
  • Mean Corpuscular Hemoglobin (MCH) Mean Corpuscular Hemoglobin — the average amount of hemoglobin per red blood cell, used to help classify types of anemia.
  • Neutrophils (%) The percentage of your white blood cells that are neutrophils, a first-line defense against infection.
  • Folate Vitamin B9, needed for cell division, DNA synthesis, and red blood cell production. Low levels can cause a type of anemia and are important in pregnancy.
  • Mean Corpuscular Hemoglobin Concentration (MCHC) Mean Corpuscular Hemoglobin Concentration — the average concentration of hemoglobin within your red blood cells, used to help classify types of anemia.
  • Mean Corpuscular Volume Mean Corpuscular Volume — the average size of your red blood cells, a key value used to help determine the cause of anemia.
  • Monocytes (%) The percentage of your white blood cells that are monocytes, cells that help fight infection and clear damaged tissue.
  • Platelet Count Cell fragments that help your blood clot. Counted to screen for bleeding or clotting risk and various blood disorders.
  • Total Iron Binding Capacity (TIBC) Total Iron-Binding Capacity — reflects how much transferrin (the iron-carrying protein) is available in your blood, used with iron and ferritin to evaluate iron status.
  • Iron % Saturation The percentage of transferrin (your iron-carrying protein) that's currently occupied by iron — a key marker for detecting iron deficiency or overload.
  • Monocytes The number of monocytes, white blood cells that help fight infection and clear damaged cells, in your blood.
  • Lymphocytes (%) The percentage of your white blood cells that are lymphocytes, key immune cells including T-cells, B-cells, and NK cells.
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.
  • Eosinophils (%) The percentage of your white blood cells that are eosinophils, elevated with allergies, asthma, or parasitic infections.
  • White Blood Cell Count (WBC) White blood cell count — the total number of white blood cells in your blood, key immune cells. Used to help detect infection, inflammation, and other blood disorders.
  • Lymphocytes The number of lymphocytes, white blood cells central to your immune response (including T-cells, B-cells, and NK cells), in your blood.
  • Red Blood Cell Count (RBC) Red blood cell count — the number of oxygen-carrying red blood cells in your blood, used to help diagnose anemia or polycythemia.
  • Eosinophils The number of eosinophils, a white blood cell type involved in allergic reactions and parasite defense, in your blood.
  • Hematocrit The percentage of your blood volume made up of red blood cells. Used to help diagnose anemia or polycythemia (excess red blood cells).
  • Hemoglobin The oxygen-carrying protein in your red blood cells. A core marker for diagnosing anemia and other blood disorders.
  • Ferritin Reflects your body's stored iron levels. Low levels point to iron deficiency; high levels can indicate iron overload or, since it's also an inflammation marker, other conditions.
  • Iron, Total Measures the iron circulating in your blood, used along with other markers (like ferritin and TIBC) to evaluate for iron deficiency or overload.
  • Neutrophils The number of neutrophils, the most abundant white blood cell type and a first-line defense against infection, in your blood.

Micronutrients, B-Vitamin Panel

 $317.99

This comprehensive test measures levels of B-vitamins in your body, essential for energy, brain function, and cell metabolism. It includes tests for Folate (B9), Vitamin B12, B2 (Riboflavin), B3 (Niacin), B5 (Pantothenic Acid), B6 (Pyridoxine), and B1 (Thiamine). Knowing your B-vitamin levels is crucial for addressing deficiencies that can lead to fatigue, anemia, immune system issues, and neurological problems.

Sample type
Serum
Avg. sample processing time
5 Business days
Require fasting
Yes
Biomarkers
  • Vitamin B3 (Nicotinic Acid)
  • Folate Vitamin B9, needed for cell division, DNA synthesis, and red blood cell production. Low levels can cause a type of anemia and are important in pregnancy.
  • Vitamin B2 (Riboflavin)
  • Vitamin B5 (Pantothenic Acid)
  • Vitamin B1 (Thiamine) Thiamine, a B vitamin essential for energy metabolism and nerve function.
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.
  • Vitamin B6 A B vitamin involved in amino acid metabolism, red blood cell production, and nervous system function.

Vitamin B12 & Folate

 $30.99

Vitamin B12 & Folate are two essential B vitamins critical for red blood cell formation, DNA synthesis, and neurological function. Testing both helps evaluate causes of anemia, fatigue, or cognitive changes, and is important in assessing overall methylation and metabolic health.

Sample type
Serum
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Folate Vitamin B9, needed for cell division, DNA synthesis, and red blood cell production. Low levels can cause a type of anemia and are important in pregnancy.
  • Vitamin B12 A vitamin essential for nerve function and red blood cell production. Low levels can cause fatigue, neurological symptoms, and a type of anemia.
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