Immunoglobulin G Subclass 3 details
What Immunoglobulin G Subclass 3 shows
Immunoglobulin G (IgG) is the main antibody type in your blood and is divided into four subclasses. IgG3 makes up only a small share of total IgG but is very effective at activating complement, part of the immune defence system, and is important in early responses to viruses and protein antigens. It is measured to help evaluate your immune system when you have recurrent infections, especially of the airways. A low IgG3 level can point to a subclass deficiency, while a high level can reflect ongoing infection or inflammation. Because isolated low subclass levels are not always significant, results are interpreted alongside total IgG, the other subclasses, and vaccine responses.
Tests that include Immunoglobulin G Subclass 3
Measurement of IgG subclasses may be helpful in the management and understanding of immunodeficiency diseases, hypersensitivity states, and conditions involving susceptibility to infection.
- Immunoglobulin G (IgG) Your most abundant antibody class, providing long-term immune memory against past infections. Low levels can point to an immune deficiency.
- Immunoglobulin G Subclass 1 Measures IgG1, the most abundant of the four IgG antibody subclasses, to help evaluate immune function in people with frequent or unusual infections.
- Immunoglobulin G Subclass 2 Measures IgG2, the IgG antibody subclass important for fighting bacteria with sugar coatings, to help evaluate immune function in people with recurrent infections.
- Immunoglobulin G Subclass 3 Measures IgG3, an IgG antibody subclass that is especially active against viruses and in activating the immune system, to help evaluate recurrent infections.
- Immunoglobulin G Subclass 4 A subclass of IgG antibodies. Elevated levels are associated with IgG4-related disease, a rare inflammatory condition that can affect multiple organs.
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