Immunoglobulin G Subclass 1 details
What Immunoglobulin G Subclass 1 shows
Immunoglobulin G (IgG) is the main antibody type in your blood and is divided into four subclasses. IgG1 is the largest, making up most of your total IgG, and is especially important in responses to protein antigens, such as those from many viruses and bacterial toxins. It is measured to help evaluate your immune system when you have recurrent or unusual infections. A low IgG1 level usually lowers total IgG as well and can point to an antibody deficiency. A high level can reflect chronic infection, inflammation, or an autoimmune condition. Subclass results are interpreted alongside total IgG, the other subclasses, and how well you respond to vaccines.
Tests that include Immunoglobulin G Subclass 1
Measurement of IgG subclasses may be helpful in the management and understanding of immunodeficiency diseases, hypersensitivity states, and conditions involving susceptibility to infection.
- Immunoglobulin G (IgG) Your most abundant antibody class, providing long-term immune memory against past infections. Low levels can point to an immune deficiency.
- Immunoglobulin G Subclass 1 Measures IgG1, the most abundant of the four IgG antibody subclasses, to help evaluate immune function in people with frequent or unusual infections.
- Immunoglobulin G Subclass 2 Measures IgG2, the IgG antibody subclass important for fighting bacteria with sugar coatings, to help evaluate immune function in people with recurrent infections.
- Immunoglobulin G Subclass 3 Measures IgG3, an IgG antibody subclass that is especially active against viruses and in activating the immune system, to help evaluate recurrent infections.
- Immunoglobulin G Subclass 4 A subclass of IgG antibodies. Elevated levels are associated with IgG4-related disease, a rare inflammatory condition that can affect multiple organs.
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