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HLA-DRB1 details

Description

HLA-DRB1 is a gene in the HLA system used both for tissue typing in transplant matching, where a close match between donor and recipient improves outcomes, and in research and clinical contexts examining autoimmune disease risk โ€” certain HLA-DRB1 variants are associated with increased risk of conditions like rheumatoid arthritis and type 1 diabetes. As with other HLA associations, carrying a particular variant increases statistical risk but doesn't predict with certainty whether someone will develop a given condition.

  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with HLA-DRB1

Explore available tests to better understand your results and gain deeper insights into your health.

Panel

HLA-DRB1, DQB1, Intermediate Resolution

$685.49

HLA typing is used to match donors and recipients for bone marrow and solid organ transplantation.

Sample type
Whole Blood
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • HLA-DQB1 A genetic marker used in celiac disease risk assessment and in tissue-typing for organ/stem cell transplant matching.
  • HLA-DRB1 A genetic marker used in tissue typing for transplant matching and studied in relation to autoimmune disease risk, including rheumatoid arthritis.

HLA Intermediate Resolution DR1/3/4/5, DQ

$768.99

This test identifies a patient's HLA DRB1/3/4/5 and DQB1 genotypes.

Sample type
Whole Blood
Avg. sample processing time
4 Business days
Require fasting
No
Biomarkers
  • HLA-DQB1 A genetic marker used in celiac disease risk assessment and in tissue-typing for organ/stem cell transplant matching.
  • HLA-DRB1 A genetic marker used in tissue typing for transplant matching and studied in relation to autoimmune disease risk, including rheumatoid arthritis.
  • HLA-DRB3 A genetic marker used in HLA tissue typing, relevant to transplant matching and certain autoimmune and neurological associations.
  • HLA-DRB4 A genetic marker used in HLA tissue typing, relevant to transplant matching and certain autoimmune associations.
  • HLA-DRB5 A genetic marker used in HLA tissue typing, relevant to transplant matching and certain autoimmune associations.

HLA Intermediate Resolution DR1/3/4/5, DQ (Allele-Resolved DRB3/4/5)

$963.49

This test identifies a patient's HLA DRB1/3/4/5 and DQB1 genotypes.

Sample type
Whole Blood
Avg. sample processing time
5 Business days
Require fasting
No
Biomarkers
  • HLA-DQB1 A genetic marker used in celiac disease risk assessment and in tissue-typing for organ/stem cell transplant matching.
  • HLA-DRB1 A genetic marker used in tissue typing for transplant matching and studied in relation to autoimmune disease risk, including rheumatoid arthritis.
  • HLA DRB3-1
  • HLA DRB3-2
  • HLA DRB4-1
  • HLA DRB4-2
  • HLA DRB5-1
  • HLA DRB5-2
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