HLA-DRB1 details
What HLA-DRB1 shows
HLA-DRB1 is a gene in the HLA system used both for tissue typing in transplant matching, where a close match between donor and recipient improves outcomes, and in research and clinical contexts examining autoimmune disease risk — certain HLA-DRB1 variants are associated with increased risk of conditions like rheumatoid arthritis and type 1 diabetes. As with other HLA associations, carrying a particular variant increases statistical risk but doesn't predict with certainty whether someone will develop a given condition.
Tests that include HLA-DRB1
HLA typing is used to match donors and recipients for bone marrow and solid organ transplantation.
- HLA-DQB1 A genetic marker used in celiac disease risk assessment and in tissue-typing for organ/stem cell transplant matching.
- HLA-DRB1 A genetic marker used in tissue typing for transplant matching and studied in relation to autoimmune disease risk, including rheumatoid arthritis.
This test identifies a patient's HLA DRB1/3/4/5 and DQB1 genotypes.
- HLA-DQB1 A genetic marker used in celiac disease risk assessment and in tissue-typing for organ/stem cell transplant matching.
- HLA-DRB1 A genetic marker used in tissue typing for transplant matching and studied in relation to autoimmune disease risk, including rheumatoid arthritis.
- HLA-DRB3 A genetic marker used in HLA tissue typing, relevant to transplant matching and certain autoimmune and neurological associations.
- HLA-DRB4 A genetic marker used in HLA tissue typing, relevant to transplant matching and certain autoimmune associations.
- HLA-DRB5 A genetic marker used in HLA tissue typing, relevant to transplant matching and certain autoimmune associations.
This test identifies a patient's HLA DRB1/3/4/5 and DQB1 genotypes.
- HLA-DQB1 A genetic marker used in celiac disease risk assessment and in tissue-typing for organ/stem cell transplant matching.
- HLA-DRB1 A genetic marker used in tissue typing for transplant matching and studied in relation to autoimmune disease risk, including rheumatoid arthritis.
- HLA DRB3-1 The first of two reported HLA-DRB3 allele results from HLA typing, describing an inherited immune gene used in transplant matching and some disease-association studies.
- HLA DRB3-2 The second of two reported HLA-DRB3 allele results from HLA typing, describing an inherited immune gene used in transplant matching and some disease-association studies.
- HLA DRB4-1 The first of two reported HLA-DRB4 allele results from HLA typing, describing an inherited immune gene used in transplant matching and some disease-association studies.
- HLA DRB4-2 The second of two reported HLA-DRB4 allele results from HLA typing, describing an inherited immune gene used in transplant matching and some disease-association studies.
- HLA DRB5-1 The first of two reported HLA-DRB5 allele results from HLA typing, describing an inherited immune gene used in transplant matching and some disease-association studies.
- HLA DRB5-2 The second of two reported HLA-DRB5 allele results from HLA typing, describing an inherited immune gene used in transplant matching and some disease-association studies.
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