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Complement C4a details

Description

C4a is a small fragment released when complement protein C4 is activated during an immune or inflammatory response, offering a more direct look at current complement system activation than a standard C4 level (which reflects available, unconsumed complement). It's a more specialized test used in certain complex inflammatory or autoimmune evaluations rather than routine screening. Elevated levels generally indicate active complement activation, consistent with an ongoing inflammatory or immune-complex-related process.

  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Complement C4a

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Complement C4a

$239.49

Complement 43a is a protein fragment produced during activation of the complement system, a key part of the immune response. Measuring C4a can help evaluate immune activation and inflammation, and may be useful in investigating autoimmune or inflammatory conditions.

Sample type
Plasma
Avg. sample processing time
7 Business days
Require fasting
No
Biomarkers
  • Complement C4a An activation fragment produced when complement protein C4 is triggered. Reflects how active your complement immune pathway currently is.

Panel

CIRS Panel

$853.49

The CIRS panel measures markers associated with Chronic Inflammatory Response Syndrome (CIRS). It aids in evaluating systemic inflammation and immune dysregulation, facilitating accurate diagnosis and tailored treatment plans for patients with CIRS-related conditions.

Sample type
Plasma Serum
Avg. sample processing time
13 Business days
Require fasting
No
Biomarkers
  • Antidiuretic Hormone Also called vasopressin, this hormone helps your kidneys regulate how much water your body retains. Abnormal levels are linked to conditions affecting fluid balance, like diabetes insipidus or SIADH.
  • Complement C4a An activation fragment produced when complement protein C4 is triggered. Reflects how active your complement immune pathway currently is.
  • Leptin A hormone released by fat cells that helps regulate appetite and energy balance. Levels generally rise with increased body fat.
  • Matrix Metalloproteinase-9 (MMP-9) An enzyme involved in breaking down tissue, including artery plaque, and contributing to inflammation. Studied in cardiovascular and certain chronic inflammatory conditions.
  • Melanocyte-Stimulating Hormone (MSH) A pituitary-derived hormone involved in skin pigmentation and, more recently, studied for roles in appetite and inflammation regulation.
  • Osmolality Measures the concentration of dissolved particles in your blood, reflecting hydration and fluid balance.
  • Vascular Endothelial Growth Factor (VEGF) A signaling protein that promotes new blood vessel growth. Studied in cancer, wound healing, and certain inflammatory or eye conditions.
  • C3A Desarg Fragment
  • Transforming Growth Factor Beta 1
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