Histamine Release (Chronic Urticaria) Blood Test
Compare labs
| Feature |
Labcorp
|
Quest Diagnostics
|
|---|---|---|
| Price | Coming soon | $131.49 |
| Results in | — | ~5 business days |
| Sample type | — | Blood Serum |
| Require fasting | — | No |
About the test
Chronic Urticaria (CU) is a common skin disorder affecting 1 to 6% of the general population. It is characterized by repeated occurrence of short-lived cutaneous wheals accompanied by redness and itching. Autoimmune urticaria is defined by the presence of a functional IgG antibody to high-affinity IgE receptor (Fc epsilon RI alpha) or IgE. These antibodies trigger mast cell and basophil degranulation by the engagement of Fc epsilon receptor. Functional IgG antibody to the receptor has been identified in approximately 30-40% of patients with CU, and anti IgE antibody has been identified in another 5%-10%.
Included biomarkers & Reference ranges
| Biomarker | Reference range |
|---|---|
| Fc Epsilon Receptor (RI + RII) Antibody Looks for autoantibodies against IgE receptors on immune cells, which can trigger histamine release and help explain some cases of chronic hives. | — |
Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.
Preparation
- Avoid taking calcineurin inhibitors for 72 hours prior to draw.
How it works
- 1. Order online No referral or insurance
- 2. Get a requisition By email in 24–72 hours
- 3. Visit a draw center Bring a matching photo ID
- 4. Get results Securely by email
- These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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