This test is crucial for understanding the autoimmune response in systemic lupus erythematosus (SLE), a condition where the body's immune system mistakenly attacks its own tissues. About 90% of people with SLE show positive results for this test, indicating their immune system is reacting to nucleosomes, which are components of the cell's nucleus.
What patients is this test right for?
This test is particularly important for individuals suspected of having SLE, given its high reactivity rate in those diagnosed with the condition.
Symptoms of SLE can vary widely but often include:
- Joint pain and swelling
- Skin rashes, particularly those that worsen with sun exposure
- Fatigue
- Fever
- Chest pain when breathing deeply
- Headaches, confusion, and memory loss