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Antiphospholipid Antibody Panel Blood Test

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Feature Labcorp Quest Diagnostics
Price Coming soon $369.49
Results in โ€” ~5 business days
Sample type โ€” Blood Plasma
Require fasting โ€” No

About the test

The antiphospholipid antibody syndrome (APS) is a clinical-pathologic correlation that includes a clinical event (e.g. arterial or venous thrombosis, pregnancy morbidity) and persistent positive antiphospholipid antibodies (IgM, IgG Cardiolipin or b2GPI antibodies greater than the 99th percentile; or a lupus anticoagulant). International consensus guidelines for APS suggest waiting at least 12 weeks before retesting to confirm antibody persistence. The Systemic Lupus International Collaborating Clinics immunological classification criteria for systemic lupus erythematosus (SLE) include testing for isotype IgA, which has yet to be incorporated into APS criteria. Low level antiphospholipid antibodies may sometimes be detected in the setting of infection, drug therapy or aging.

Note: Target-specific anticoagulant therapy (anti-Xa medications, direct thrombin inhibitors) may cause false positive results for Lupus anticoagulant testing but do not impact the Cardiolipin, B2GPI and Phosphatidylserine-Prothrombin antibody testing.

Included biomarkers & Reference ranges

Biomarker Reference range
Beta-2-Glycoprotein I Antibody (IgA) Measures IgA antibodies against beta-2-glycoprotein I, one of the antiphospholipid antibodies, used to evaluate antiphospholipid syndrome and causes of blood clots. โ€”
Beta-2-Glycoprotein I Antibody (IgG) Measures IgG antibodies against beta-2-glycoprotein I, one of the antiphospholipid antibodies, used to evaluate antiphospholipid syndrome and causes of blood clots. โ€”
Beta-2-Glycoprotein I Antibody (IgM) Measures IgM antibodies against beta-2-glycoprotein I, one of the antiphospholipid antibodies, used to evaluate antiphospholipid syndrome and causes of blood clots. โ€”
Cardiolipin Antibody (IgA) An antibody that attacks the body's own phospholipids (IgA type). One of the markers used to help diagnose antiphospholipid syndrome, which raises the risk of blood clots and pregnancy complications. โ€”
Cardiolipin Antibody (IgG) An antibody that attacks the body's own phospholipids (IgG type). One of the markers used to help diagnose antiphospholipid syndrome, which raises the risk of blood clots and pregnancy complications. โ€”
Cardiolipin Antibody (IgM) An antibody that attacks the body's own phospholipids (IgM type). One of the markers used to help diagnose antiphospholipid syndrome, which raises the risk of blood clots and pregnancy complications. โ€”
Phosphatidylserine/ Prothrombin Antibody (IgG) Measures IgG antibodies against the phosphatidylserine/prothrombin complex, used alongside other antiphospholipid tests when looking at clotting or pregnancy-loss risk. โ€”
Phosphatidylserine/ Prothrombin Antibody (IgM) Measures IgM antibodies against the phosphatidylserine/prothrombin complex, used alongside other antiphospholipid tests when looking at clotting or pregnancy-loss risk. โ€”

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

How it works

  1. 1. Order online No referral or insurance
  2. 2. Get a requisition By email in 24โ€“72 hours
  3. 3. Visit a draw center Bring a matching photo ID
  4. 4. Get results Securely by email
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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