Symmetric Dimethylarginine (SDMA) details
What Symmetric Dimethylarginine (SDMA) shows
Symmetric dimethylarginine (SDMA) is a by-product released when proteins in your cells are broken down. It is removed from the body almost entirely by the kidneys, so its blood level closely follows kidney filtration. It is often measured with ADMA, a related compound that affects nitric oxide, which helps blood vessels relax. SDMA is measured to look at kidney function and, in research, cardiovascular risk. A higher result usually points to reduced kidney filtration and has been linked with higher cardiovascular risk. A lower result is generally not a concern. It is interpreted alongside creatinine, eGFR and ADMA rather than on its own.
Tests that include Symmetric Dimethylarginine (SDMA)
This test measures levels of ADMA (asymmetric dimethylarginine) and SDMA (symmetric dimethylarginine) in the blood, which are compounds made in your body as proteins are degraded. ADMA and SDMA are indicators that may help in assessing the risk for cardiovascular disease in individuals with multiple risk factors.
- Asymmetric Dimethylarginine (ADMA) Asymmetric dimethylarginine is a natural compound that blocks nitric oxide production in blood vessels, measured as a marker of blood vessel health and cardiovascular risk.
- Symmetric Dimethylarginine (SDMA) Measures symmetric dimethylarginine (SDMA), a substance cleared by the kidneys, studied as a marker of kidney function and cardiovascular risk.
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