Lambda Light Chain, Free details
What Lambda Light Chain, Free shows
Antibodies are made of heavy and light chains, and light chains come in two types, kappa and lambda. Plasma cells normally make slightly more light chains than they need, and the extra circulate freely in the blood. This test measures free lambda light chains in serum and is used, together with free kappa and their ratio, to help evaluate and monitor plasma cell disorders such as multiple myeloma and AL amyloidosis. A high free lambda level can come from an abnormal group of plasma cells, but it also rises with reduced kidney function, inflammation, and broad immune activation. For that reason, it is interpreted mainly through the kappa/lambda ratio and other protein tests.
Tests that include Lambda Light Chain, Free
The Kappa/Lambda Light Chains, Free with Ratio, Serum test measures the amount of kappa and lambda free light chains (FLCs) in the blood and calculates the kappa to lambda ratio. It is used to assist in the diagnosis of plasma cell disorders, including multiple myeloma, primary amyloidosis, monoclonal gammopathy of unknown significance (MGUS), Waldenström’s macroglobulinemia, and related disorders. It is also used to monitor disease activity and treatment [1].
- Kappa/Lambda Light Chains Free With Ratio A calculated ratio of free kappa to free lambda light chains in serum, used to help detect and monitor plasma cell disorders such as multiple myeloma.
- Kappa Light Chain, Free Measures free kappa light chains in serum, small antibody pieces made by plasma cells, used with lambda light chains to help evaluate plasma cell disorders.
- Lambda Light Chain, Free Measures free lambda light chains in serum, small antibody pieces made by plasma cells, used with kappa light chains to help evaluate plasma cell disorders.
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