Itraconazole details
What Itraconazole shows
Itraconazole is an antifungal medicine used to treat and prevent infections such as aspergillosis and other fungal diseases. How much reaches the blood varies widely between people, depending on the formulation, food, stomach acid, and other medicines. This test measures itraconazole in serum, usually together with its active breakdown product hydroxyitraconazole, as part of therapeutic drug monitoring. A low level can mean the medicine is not being absorbed well, a dose is being missed, or another medicine is lowering it, which may reduce effectiveness. A high level can raise the chance of side effects. Timing relative to your last dose matters, so results are interpreted by your prescriber.
Tests that include Itraconazole
The antifungal drug itraconazole is active in the treatment of aspergillosis, blastomycosis, histoplasmosis, sporotrichosis, and onychomycosis. It is a protein-bound drug and thus has negligible CSF penetration. It may also be utilized in the treatment of systemic candidiasis and cryptococcosis, especially when other drugs are contraindicated or ineffective. The chronic nature of fungal infections demands constant monitoring of itraconazole levels within a patient to ensure that adequate therapeutic levels of the drug are administered, absorbed and subsequently excreted
- Hydroxyitraconazole The main active breakdown product of the antifungal medicine itraconazole, measured in serum to help check that drug levels are in an effective range.
- Itraconazole Measures the level of the antifungal medicine itraconazole in serum, used to check that you are absorbing enough of it for treatment to work.
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