Calcitriol (1,25 di-OH Vitamin D) details
What Calcitriol (1,25 di-OH Vitamin D) shows
Calcitriol is the active, hormone form of vitamin D — the form that actually does the work of helping your body absorb calcium from food and regulate calcium levels, after your kidneys convert inactive vitamin D (25-OH vitamin D) into this active form. Unlike standard 25-OH vitamin D testing, which reflects your overall vitamin D stores, calcitriol testing is used less often and mainly in specific situations: evaluating certain calcium disorders, kidney disease (since the kidneys are needed to make calcitriol), sarcoidosis or other granulomatous diseases that can produce calcitriol abnormally, and some rare genetic conditions affecting vitamin D metabolism. For routine vitamin D status, standard 25-OH vitamin D testing is the appropriate test, not this one.
Normal ranges
Typical adult range
18–72 pg/mL
Most labs report a range close to this
Hormunity optimal range
35–55 pg/mL
A narrower functional target
Each lab sets its own reference range. Always compare your result with the range printed on your report, and review it with a healthcare provider.
Tests that include Calcitriol (1,25 di-OH Vitamin D)
This test measures 1,25-dihydroxyvitamin D (calcitriol), the active form of Vitamin D in the body. It is used to aid in the diagnosis of primary hyperparathyroidism, hypoparathyroidism, pseudohypoparathyroidism, renal osteodystrophy, and vitamin D-resistant rickets.
- Calcitriol (1,25 di-OH Vitamin D) The active, hormone form of vitamin D that directly regulates calcium absorption. Tested less often than 25-OH vitamin D, mainly for kidney or calcium-regulation disorders.
This test checks the active form of vitamin D in your body. It's mainly used to help figure out why someone has low calcium levels and to keep an eye on people with bone problems due to kidney disease or those with chronic kidney failure. However, it's not the right test for finding out if you're low on vitamin D or for tracking how well vitamin D supplements are working. For those needs, the 25-hydroxyvitamin D test is recommended.
- Calcitriol (1,25 di-OH Vitamin D) The active, hormone form of vitamin D that directly regulates calcium absorption. Tested less often than 25-OH vitamin D, mainly for kidney or calcium-regulation disorders.
- Vitamin D2, 1,25 (OH)2 Measures the active, hormone form of vitamin D made from vitamin D2, reported as part of a total 1,25-dihydroxyvitamin D (calcitriol) result.
- Vitamin D3, 1,25 (OH)2 Measures the active, hormone form of vitamin D made from vitamin D3, reported as part of a total 1,25-dihydroxyvitamin D (calcitriol) result.
Vitamin D originating from dietary and endogenous sources is converted to 25-hydroxyvitamin D in the liver, and subsequently to 1, 25-dihydroxyvitamin D in the kidney. Measurement of both the 1, 25-Dihydroxy and 25-Hydroxy forms provide insights into a variety of medical conditions such Vitamin D status in renal failure, differential diagnosis of primary, secondary and tertiary hyperparathyroidism. Differential diagnosis of hypercalcemia and type I and II inherited rickets.
- Vitamin D, 25-OH, Total The combined measure of both major forms of vitamin D (D2 and D3) in your blood — the standard test used to assess overall vitamin D status.
- Calcitriol (1,25 di-OH Vitamin D) The active, hormone form of vitamin D that directly regulates calcium absorption. Tested less often than 25-OH vitamin D, mainly for kidney or calcium-regulation disorders.
- 25-OH Hydroxy Vitamin D (Cholecalciferol D3) The vitamin D3 portion of your 25-hydroxyvitamin D, coming from sunlight on your skin, animal foods and most supplements, used to assess vitamin D status.
- 25-OH Hydroxy Vitamin D (Ergocalciferol D2) The vitamin D2 portion of your 25-hydroxyvitamin D, which comes mainly from plant-based sources and prescription or some over-the-counter supplements.
- Vitamin D2, 1,25 (OH)2 Measures the active, hormone form of vitamin D made from vitamin D2, reported as part of a total 1,25-dihydroxyvitamin D (calcitriol) result.
- Vitamin D3, 1,25 (OH)2 Measures the active, hormone form of vitamin D made from vitamin D3, reported as part of a total 1,25-dihydroxyvitamin D (calcitriol) result.
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