Apolipoprotein B/Apolipoprotein A-1 details
What Apolipoprotein B/Apolipoprotein A-1 shows
The ApoB/ApoA-1 ratio is calculated by dividing your apolipoprotein B level by your apolipoprotein A-1 level. ApoB is the main protein on LDL and other particles that can deposit cholesterol in artery walls, with one ApoB per particle, while ApoA-1 is the main protein on HDL, which helps remove cholesterol. The ratio gives a single picture of the balance between these two types of particles. A higher ratio points to a balance that favours cholesterol buildup in the arteries and a higher cardiovascular risk, while a lower ratio is more favourable. It is one of several lipid markers and is read alongside your cholesterol results, blood pressure, family history and other risk factors.
Tests that include Apolipoprotein B/Apolipoprotein A-1
Apolipoprotein A1 is the primary protein associated with HDL cholesterol. Like HDL cholesterol, increased concentrations are associated with reduced risk of cardiovascular disease. Apolipoprotein B-100 is the primary protein associated with LDL cholesterol and other lipid particles. Like LDL cholesterol, increased concentrations are associated with increased risk of cardiovascular disease. The ratio of these two apolipoproteins correlates with risk of cardiovascular disease.
- Apolipoprotein A-1 The main protein component of HDL ('good') cholesterol. Higher levels are generally associated with better cardiovascular protection.
- Apolipoprotein B The main protein found on LDL and other 'bad' cholesterol particles. Considered a strong indicator of cardiovascular risk, since each particle carries one ApoB molecule.
- Apolipoprotein B/Apolipoprotein A-1 A ratio calculated from apolipoprotein B and apolipoprotein A-1, comparing cholesterol-carrying particles that harm arteries with those that protect them, to assess cardiovascular risk.
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