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DUTCH Plus®

$639.00

The DUTCH Plus is a comprehensive dried urine and saliva test that maximizes the available information from sex and adrenal hormone production and metabolism. With easy, at-home sample collection over the course of one day, providers can gain insights into the overall diurnal pattern of free cortisol and cortisone, along with the total distribution of cortisol metabolites. This test offers further insight by including organic acid testing, which evaluates potential nutritional deficiencies, oxidative stress, gut dysbiosis, melatonin levels, and neuroinflammation.

SKU: PADUPL Category: Brand:

Description

The DUTCH Plus™ goes a step further by adding salivary cortisol awakening response (CAR) testing — capturing your body’s stress response at the very start of your day. This extra layer of insight helps you understand not just what your hormones look like, but how your body reacts to stress each morning, revealing patterns of resilience or burnout that other tests miss.
Why This Matters
The first hour after waking is one of the most powerful stress “windows” your body has. A healthy cortisol awakening response helps:

  • Turn on brain alertness
  • Regulate immune activity
  • Prepare the body for daily stressors

If your CAR is blunted, exaggerated, or delayed, it can be a red flag for:

  • Chronic stress burnout
  • PTSD and trauma patterns
  • Inflammatory or autoimmune conditions
  • Depression or chronic fatigue
  • Cognitive decline risk

What DUTCH Plus™ Measures
Everything in the DUTCH Complete plus:

  • Salivary cortisol awakening response (CAR) — multiple samples right after waking to capture the natural spike and recovery pattern.
  • Full diurnal cortisol curve — saliva + urine mapping to see adrenal rhythm all day.
  • Comprehensive sex hormone panel — estrogen, progesterone, testosterone, and all metabolites.
  • Estrogen metabolism — including the protective 2-OH, proliferative 16-OH, and potentially harmful 4-OH pathways.
  • Androgen metabolism — balance between alpha and beta pathways affecting strength, mood, and skin.
  • Melatonin — night-time production for sleep regulation.
  • Organic acid markers — B-vitamins, neurotransmitter metabolites, oxidative stress indicators.

When to Choose DUTCH Plus™ Over DUTCH Complete

  • Chronic stress or burnout symptoms
  • Unexplained fatigue despite rest
  • Mood disorders (anxiety, depression)
  • Autoimmune or inflammatory conditions
  • Suspected PTSD or trauma-driven stress patterns
  • Hormonal imbalance with major energy swings

How to Test

  • Cycling women: Collect between days 19–21 of your cycle (mid-luteal phase) for best accuracy.
  • Non-cycling women, men, teens 14+: Test any day.
  • Collection: Four dried urine samples across the day, plus five salivary samples within the first hour after waking and throughout the day.
  • Let samples dry (urine strips) or seal saliva tubes, then ship to the lab.

Order your DUTCH Plus™ today — and discover not just what your hormones look like, but how your body responds to stress every single morning.

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