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Neurofilament Light Chain (NfL), Plasma details

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Neurofilament Light Chain (NfL), Plasma

Labcorp

Broadest draw-site network nationwide.

This test is coming soon at Labcorp.

Neurofilament Light Chain (NfL), Plasma

Quest Diagnostics

Same-day appointments in most metros.

Sample type
Plasma
Avg. sample processing time
5 Business days
Require fasting
No

BiomarkersQuest Diagnostics biomarkers

  • Neurofilament Light Chain A protein released when nerve cells are damaged. An emerging marker studied in neurological conditions like multiple sclerosis and neurodegenerative disease.
$333.49

Description

Neurofilament light (NfL) is an intermediate filament protein found specifically in the neuronal cytoskeleton. It can be released into the extracellular space through axonal degradation, and it has been shown that varying NfL levels are an indicator of neuroaxonal damage, irrespective of the cause, and can therefore be associated with a variety of neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, frontotemporal dementia, or Alzheimer's disease, as well as acute situations such as traumatic brain injury and others. NfL is thus considered a promising biomarker for, disease activity, progression, prognosis, and monitoring effectiveness of therapies. As NfL can be measured in both cerebrospinal fluid (CSF) and blood, it holds great potential for routine clinical use.

Included biomarkers

Biomarkers

  • Neurofilament Light Chain A protein released when nerve cells are damaged. An emerging marker studied in neurological conditions like multiple sclerosis and neurodegenerative disease.

Preparation

Labcorp

This test is coming soon at Labcorp.

Quest Diagnostics
  • Stop biotin consumption at least 72 hours prior to sample collection.
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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