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Lynch Syndrome Panel Blood Test

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Feature Labcorp Quest Diagnostics
Price Coming soon $4,155.49
Results in โ€” ~5 business days
Sample type โ€” Blood Whole Blood
Require fasting โ€” No

About the test

Lynch syndrome is a leading cause of inherited colon cancer, affecting 2% to 4% of all cases of colorectal and endometrial cancer. This test looks for specific genetic changes (pathogenic variants) in the MLH1, MSH2, MSH6, PMS2, and EPCAM genes that can indicate Lynch syndrome.

Who should consider this test?

This test is particularly important for individuals with a family history of colon cancer or those who have been diagnosed with colorectal or endometrial cancer at a young age.

Included biomarkers & Reference ranges

Biomarker Reference range
Epcam A genetic test looking for changes in the EPCAM gene, which can switch off the neighboring MSH2 gene and are a recognised cause of Lynch syndrome. โ€”
MLH1 Looks for inherited changes in the MLH1 gene, a DNA mismatch repair gene, as part of testing for Lynch syndrome. โ€”
MSH2 Looks for inherited changes in the MSH2 gene, a DNA mismatch repair gene, as part of testing for Lynch syndrome. โ€”
MSH6 Looks for inherited changes in the MSH6 gene, a DNA mismatch repair gene, as part of testing for Lynch syndrome. โ€”
PMS2 Genetic test of the PMS2 gene, which helps repair DNA copying errors; harmful variants are one cause of Lynch syndrome and raised cancer risk. โ€”

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

How it works

  1. 1. Order online No referral or insurance
  2. 2. Get a requisition By email in 24โ€“72 hours
  3. 3. Visit a draw center Bring a matching photo ID
  4. 4. Get results Securely by email
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Consultations

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