Juvenile Polyposis Panel (BMPR1A and SMAD4) Blood Test

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Feature	Labcorp	Quest Diagnostics
Price	Coming soon	$3,935.49
Results in	—	~5 business days
Sample type	—	Blood Whole Blood
Require fasting	—	No

About the test

This test looks for specific genetic changes in the BMPR1A and SMAD4 genes that are linked to Juvenile Polyposis syndrome (JPS). People with JPS have a higher chance of developing colorectal cancer (40-50%) and stomach cancer (up to 21%, especially if they have many polyps in their stomach). They also have a slightly increased risk for cancers of the small intestine and pancreas. Identifying these genetic mutations can help manage and reduce the risk of cancer.

Who should consider this test?

This test is particularly important for individuals who have a family history of JPS or who have symptoms that could suggest JPS.

Included biomarkers & Reference ranges

Biomarker	Reference range
Bmpr1a A genetic test for inherited variants in the BMPR1A gene, which are a known cause of juvenile polyposis syndrome, a condition causing digestive tract polyps.	—
Smad4 Genetic test of the SMAD4 gene, a tumor suppressor; harmful variants cause juvenile polyposis syndrome and raise the risk of digestive tract polyps and cancer.	—

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

How it works

1. Order online No referral or insurance
2. Get a requisition By email in 24–72 hours
3. Visit a draw center Bring a matching photo ID
4. Get results Securely by email

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Consultations

Not sure how to read your results? We can help.

Schedule a consultation with a Hormunity specialist. We’ll walk through every marker, interpret what it means for you, and map out the next steps for your care.

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