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Alpha-Gal Panel Blood Test

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Feature Labcorp Quest Diagnostics
Price Coming soon $54.49
Results in โ€” ~5 business days
Sample type โ€” Blood Serum
Require fasting โ€” No

About the test

This in vitro allergen-specific IgE panel is used to quantitatively measure an individual's IgE response to alpha-gal, an allergy component, and 3 meats (beef, pork, and lamb) that commonly trigger alpha-gal-associated meat allergy. This IgE panel may be used in conjunction with other clinical information to aid in the diagnosis of alpha-gal syndrome, a severe allergic reaction to mammalian meat induced by past tick bites [1].

Most cases of alpha-gal syndrome occur in the southeastern United States because of the heavy presence of the lone star ticks. Other types of ticks also have been associated with alpha-gal syndrome in Europe, Australia, Asia, and the northern and western United States. The alpha-gal (ie. galactose-alpha-1,3-galactose) IgE test helps evaluate the etiology of meat allergies in patients with delayed onset of symptoms (3 to 6 hours after eating meat) [1,2]. IgE antibodies to alpha-gal are the likely mediator of anaphylactic reactions in individuals who develop hypersensitivities to beef, pork and/or lamb as adults [2].

The results of this panel should be interpreted in the context of pertinent clinical and family history and physical examination findings. More specific information about each allergen included in this panel can be found on the Quest Diagnostics Directory Page.

References

  1. Alpha-gal syndrome. Center for Disease Control and Prevention. Updated March 28, 2022. Accessed May 21, 2022. https://www.cdc.gov/ticks/alpha-gal/index.html

  2. o215 Alpha-Gal. Thermo Fisher Scientific. Accessed June 13, 2022. https://www.thermofisher.com/diagnostic-education/hcp/us/en/resource-center/allergen-encyclopedia/allergen-component.html?key=o215

Included biomarkers & Reference ranges

Biomarker Reference range
Beef (f27) IgE Measures IgE antibodies to beef, used to check for allergic sensitization that may explain your symptoms. โ€”
Galactose-Alpha-1,3-Galactose (Alpha-Gal) IgE Measures IgE antibodies to alpha-gal, a sugar found in red meat, used to investigate delayed allergic reactions linked to tick bites. โ€”
Lamb (f88) IgE Measures IgE antibodies to lamb meat to check for allergic sensitization, including as part of testing for alpha-gal (red meat) allergy. โ€”
Pork (f26) IgE Measures IgE antibodies to pork, a meat allergen, often tested alongside alpha-gal to look into delayed reactions after eating red meat. โ€”

Reference ranges vary by lab, age, and sex (M/F). Your report shows your exact range. Click any biomarker to see its optimal range and what your results mean.

How it works

  1. 1. Order online No referral or insurance
  2. 2. Get a requisition By email in 24โ€“72 hours
  3. 3. Visit a draw center Bring a matching photo ID
  4. 4. Get results Securely by email
  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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