TSH Receptor Binding Antibody (TRAb) details
What TSH Receptor Binding Antibody (TRAb) shows
TSH receptor binding antibodies (TRAb) are autoantibodies that attach to the receptor TSH normally uses to control the thyroid gland. Some of these antibodies switch the thyroid on, causing it to make too much hormone, while others can block it. This test is mainly used when your thyroid is overactive, to help tell Graves' disease apart from other causes, and in pregnancy for people with current or past Graves' disease. A positive result supports an autoimmune cause, most often Graves' disease. A negative result makes it less likely. The test does not show whether the antibodies stimulate or block, so it is interpreted with TSH and thyroid hormones.
Tests that include TSH Receptor Binding Antibody (TRAb)
Measurement of TRAb is used to diagnose and manage Graves' disease, neonatal hypothyroidism, and postpartum thyroid dysfunction. TRAb, which measures the ability of antibodies to inhibit TSH binding to its receptor, reflects the presence of either or both the stimulatory and inhibitory immunoglobulin classes.
- TSH Receptor Binding Antibody (TRAb) Measures antibodies that bind to the TSH receptor on the thyroid, used mainly to look into Graves' disease and some causes of overactive thyroid.
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