SARS-CoV-2 Spike Antibody, Interpretation details

This result is the interpretation, such as positive or negative, that accompanies a semi-quantitative test for total antibodies to the spike protein of SARS-CoV-2, the virus that causes COVID-19. The spike protein is the part of the virus targeted by vaccines, so these antibodies can come from either past infection or vaccination. A positive result means spike antibodies were detected, while a negative result means none were found at the test's level of detection, which can occur early after infection or as antibodies fade. This test does not diagnose a current infection, and an antibody result does not tell you how protected you are.