Plasma Renin Activity, LC/MS/MS details
What Plasma Renin Activity, LC/MS/MS shows
Renin is an enzyme released by the kidneys that starts a hormone chain controlling blood pressure, salt and fluid balance, ending with aldosterone. Plasma renin activity measures how quickly your renin generates angiotensin I, here quantified by LC/MS/MS. It is mainly measured with aldosterone to calculate the aldosterone/renin ratio, used to look for primary aldosteronism, a hormone-related cause of high blood pressure. Low renin with high aldosterone points toward that condition, while high renin can be seen with low salt intake, dehydration, kidney artery narrowing or certain medications. Posture, salt intake and many blood pressure medicines affect the result, so it is interpreted under the conditions of the test.
Tests that include Plasma Renin Activity, LC/MS/MS
The Aldosterone-renin ratio is used to screen for primary aldosteronism.
- ALDO/PRA Ratio A ratio calculated from aldosterone and plasma renin activity, used mainly to screen for primary aldosteronism as a cause of high blood pressure.
- Aldosterone, LC/MS/MS Measures aldosterone, the adrenal hormone that controls salt, potassium and blood pressure, using a precise mass spectrometry method.
- Plasma Renin Activity, LC/MS/MS Measures plasma renin activity, an enzyme that controls blood pressure and salt balance, mainly used with aldosterone to look for causes of high blood pressure.
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