Leukotriene E4, Random details
What Leukotriene E4, Random shows
Leukotriene E4 is the stable end product of cysteinyl leukotrienes, inflammatory chemicals released by mast cells and some other immune cells, and it is passed out in the urine. This test measures leukotriene E4 in a single random urine sample, usually reported relative to creatinine to correct for urine concentration. Collecting it soon after a flare of symptoms can help catch short-lived mast cell activity. It is used mainly to help evaluate mast cell activation and mastocytosis, and it can also be raised in aspirin-exacerbated respiratory disease and asthma. Some asthma medicines, such as zileuton, can lower it, so it is interpreted alongside other mediators and symptoms.
Tests that include Leukotriene E4, Random
This test is an aid to evaluate patients suspected of having systemic mastocytosis using random urine collections.
- Creatinine, Random Measures creatinine in a random urine sample, mainly used as a reference to adjust other urine results for how concentrated or dilute the sample is.
- Leukotriene E4, Random Measures leukotriene E4 in a random urine sample, a marker of inflammatory leukotriene production used mainly to help evaluate mast cell activation.
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