Leukotriene E4, 24 Hour details
What Leukotriene E4, 24 Hour shows
Leukotriene E4 is the stable end product of cysteinyl leukotrienes, inflammatory chemicals released by mast cells and some other immune cells, and it is passed out in the urine. This test measures leukotriene E4 in urine collected over a full 24 hours, which smooths out changes during the day. It is used mainly to help evaluate mastocytosis and mast cell activation, and it can also be raised in aspirin-exacerbated respiratory disease and during asthma flares. A higher result suggests increased leukotriene production. Some asthma medicines, such as zileuton, can lower it, so it is interpreted alongside tryptase, other mast cell mediators, medicines, and symptoms.
Tests that include Leukotriene E4, 24 Hour
This test is an aid to evaluate patients suspected of having systemic mastocytosis using 24-hour urine collections.
- Creatinine, 24 Hour Measures the total creatinine passed in a 24-hour urine collection, used to check the collection is complete and to calculate kidney function and other urine results.
- Leukotriene E4, 24 Hour Measures leukotriene E4 in a 24-hour urine collection, a marker of inflammatory leukotriene production used mainly to help evaluate mast cell disorders.
Not sure how to read your results? We can help.
Schedule a consultation with a Hormunity specialist. We’ll walk through every marker, interpret what it means for you, and map out the next steps for your care.
Book a specialist