Hereditary Hemochromatosis (HFE) Gene details
What Hereditary Hemochromatosis (HFE) Gene shows
The HFE gene makes a protein that helps your body sense how much iron it has and limit how much it absorbs from food. This DNA test looks for well-known HFE variants, such as C282Y and H63D, to check for an inherited tendency toward hereditary hemochromatosis, a condition in which iron slowly builds up in the body. Carrying two copies of C282Y is the pattern most strongly linked to iron overload, while other combinations carry lower or uncertain risk. The result is a lifelong genetic variant, not a level that changes. Many people with risk variants never develop iron overload, so it is interpreted alongside ferritin and transferrin saturation.
Tests that include Hereditary Hemochromatosis (HFE) Gene
This test detects variations in the HFE gene. It aids in the identification of individuals at risk for symptoms of hemochromatosis due to variants in the HFE gene. It analyzes 3 variants - C282Y, H63D, and S65C.
- Hereditary Hemochromatosis (HFE) Gene A genetic test for variants in the HFE gene, which helps control iron absorption, used to check for inherited risk of hereditary hemochromatosis (iron overload).
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