Factor II Activity details
What Factor II Activity shows
Factor II, also known as prothrombin, is a protein made by the liver that plays a central role late in the blood clotting cascade, ultimately being converted into thrombin, the enzyme that directly triggers clot formation. This test measures how well Factor II is functioning, and low activity — whether from an inherited deficiency, liver disease (since the liver makes it), vitamin K deficiency, or anticoagulant medication — can contribute to a bleeding tendency. It's typically ordered as part of a broader clotting factor workup when unexplained bleeding or an abnormal PT/INR result needs further investigation.
Tests that include Factor II Activity
This test measures factor II activity to evaluate prolonged aPTT and PT results. This test does not diagnose factor II mutations.
- Factor II Activity Measures the activity of Factor II (prothrombin), a clotting protein made in the liver. Used to evaluate bleeding or clotting disorders.
This test measures factor II activity to evaluate prolonged aPTT and PT results. This test does not diagnose factor II mutations.
- Factor II Activity Measures the activity of Factor II (prothrombin), a clotting protein made in the liver. Used to evaluate bleeding or clotting disorders.
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