F2-Isoprostane/Creatinine Ratio details
What F2-Isoprostane/Creatinine Ratio shows
F2-isoprostanes are compounds formed when free radicals damage fats in cell membranes, so their level in urine reflects oxidative stress. Because urine can be more or less concentrated depending on how much you drink, this ratio is calculated by dividing the F2-isoprostane result by the urine creatinine result, making samples easier to compare. A higher ratio suggests more oxidative damage, which can be associated with factors such as smoking, excess weight, poorly controlled blood sugar or chronic inflammation, while a lower ratio suggests less. It is a general marker rather than a sign of any specific disease, and is best interpreted alongside your health history and other test results.
Tests that include F2-Isoprostane/Creatinine Ratio
This test is considered the best method for checking oxidative stress in the body, which can be caused by a poor diet, smoking, a family history of heart disease, or high cholesterol. High levels may indicate a higher risk of hardening of the arteries (atherosclerosis) and some types of cancer.
- Creatinine, Random Measures creatinine in a random urine sample, mainly used as a reference to adjust other urine results for how concentrated or dilute the sample is.
- F2-Isoprostane/Creatinine Ratio F2-isoprostane in urine divided by urine creatinine, a corrected marker of oxidative damage to fats used to assess overall oxidative stress.
- F2-Isoprostane A marker of oxidative damage to fats in the body, measured in urine to help assess your overall level of oxidative stress.
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