Estimated GFR details
What Estimated GFR shows
Estimated GFR (eGFR) is a calculated value that estimates your glomerular filtration rate, meaning how much blood your kidneys filter each minute. In this test it is calculated from your cystatin C level, a protein cleared by the kidneys, using an equation that also takes into account factors such as age and sex. Cystatin C is less affected by muscle mass than creatinine, so it can be useful when creatinine-based estimates may be misleading. A lower eGFR suggests reduced kidney function, while a result in the expected range suggests filtration is adequate. It is an estimate, so it is interpreted alongside other kidney tests, such as urine albumin, and repeat results over time.
Tests that include Estimated GFR
This test measures the level of Cystatin C, a protein found in your body fluids, to assess kidney function. Unlike other markers, the level of Cystatin C's in the blood does not change due to infections, diet, or medication, making it a reliable indicator of how well your kidneys are filtering. The test also estimates your Glomerular Filtration Rate (eGFR), which indicates the rate at which your kidneys are filtering the blood. It's especially useful for people with unusual muscle mass or rapidly changing kidney function.
- Cystatin C An alternative marker of kidney function that, unlike creatinine, isn't affected by muscle mass — useful for a more precise eGFR estimate.
- Estimated GFR An estimate of how well your kidneys filter blood, calculated here from cystatin C along with factors such as age and sex.
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