Copper/Creatinine Ratio details
What Copper/Creatinine Ratio shows
This ratio is calculated from the copper concentration and the creatinine concentration in the same random urine sample. Creatinine is released at a fairly steady rate, so dividing copper by creatinine helps correct for how concentrated or dilute your urine happens to be. A higher ratio means more copper is being lost in the urine, which can be seen in Wilson disease, some other liver conditions and during treatment with copper-binding drugs. Creatinine output depends on muscle mass, which affects the ratio, and a 24-hour urine collection is often preferred. It is interpreted with blood copper and ceruloplasmin.
Tests that include Copper/Creatinine Ratio
Copper, Urine measures the amount of copper excreted in urine over a specific period. It is used to assess copper metabolism and help diagnose conditions like Wilson’s disease or copper toxicity.
- Copper/Creatinine Ratio Compares urine copper to urine creatinine in a random sample, correcting for how dilute the urine is, to help look at copper excretion.
- Copper, Random Measures the concentration of copper in a random urine sample, used to help look at copper handling, particularly when Wilson disease is being considered.
- Creatinine, Random Measures creatinine in a random urine sample, mainly used as a reference to adjust other urine results for how concentrated or dilute the sample is.
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