Copeptin details
What Copeptin shows
Copeptin is a small fragment released from the same precursor molecule as vasopressin, the hormone that tells your kidneys to hold on to water. Vasopressin itself is unstable and hard to measure, so copeptin is used as a reliable stand-in. It helps look at causes of excessive thirst and urination, such as vasopressin deficiency (diabetes insipidus) versus drinking large amounts of fluid, and at low sodium levels. A low level, especially during a stimulation test, can point to reduced vasopressin release, and a high level to strong release or kidney resistance. It is interpreted with sodium, osmolality and test conditions.
Tests that include Copeptin
The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is a reliable surrogate marker for arginine vasopressin (AVP).
- Copeptin Measures copeptin, a stable marker of vasopressin (antidiuretic hormone) release, to help evaluate problems with water balance and sodium levels.
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