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Coombs Direct (Direct Antiglobulin Test) details

Description

The direct Coombs test (direct antiglobulin test) checks whether antibodies or complement proteins are attached directly to the surface of your own red blood cells, which can mark those cells for premature destruction by your immune system. A positive result supports a diagnosis of autoimmune hemolytic anemia, where the body mistakenly attacks its own red blood cells, or can indicate a transfusion reaction, where the immune system is reacting to transfused blood cells, or, in newborns, hemolytic disease of the newborn caused by maternal antibodies. It's typically ordered when unexplained anemia or signs of red blood cell destruction (like jaundice or dark urine) are present.

  1. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Laboratory

Blood tests with Coombs Direct (Direct Antiglobulin Test)

Explore available tests to better understand your results and gain deeper insights into your health.

Single marker

Direct Coombs

$23.49

The Direct Coombs test (also known as the direct antiglobulin test) detects antibodies or complement proteins bound to the surface of red blood cells. It is used to help diagnose conditions like autoimmune hemolytic anemia, hemolytic disease of the newborn, or transfusion reactions.

Sample type
Whole Blood
Avg. sample processing time
2 Business days
Require fasting
No
Biomarkers
  • Coombs Direct (Direct Antiglobulin Test) Checks whether antibodies are attached to your own red blood cells, which can cause them to be destroyed. Used to help diagnose autoimmune hemolytic anemia or transfusion reactions.
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