Complement Component C1Q details
What Complement Component C1Q shows
Complement is a group of blood proteins that work with antibodies to clear infections and immune complexes. C1q starts the classical complement pathway by binding to antibodies attached to their targets. Measuring it helps look at how this pathway is working. A low level can be seen when complement is being used up, as in some autoimmune conditions such as lupus, in acquired forms of C1 inhibitor deficiency causing angioedema, or, rarely, in inherited C1q deficiency. It is interpreted alongside C3, C4, C1 inhibitor and your symptoms.
Tests that include Complement Component C1Q
The complement system is critical to the inflammatory response. C1q concentrations may be decreased in patients with acquired angioedema, immune complex induced vasculitis, and concurrent low concentrations of C1 inhibitor, carcinoma, or lymphoma.
- Complement Component C1Q Measures C1q, the first protein in the classical complement pathway, to help evaluate certain immune disorders, angioedema and immune complex conditions.
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