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ApoE Genotype details

What ApoE Genotype shows

This is a genetic test that identifies which variants (alleles) of the APOE gene you carry โ€” typically some combination of E2, E3, and E4. APOE plays a central role in how your body packages and transports cholesterol and other fats, and different variant combinations are associated with different average cardiovascular risk profiles. The E4 variant in particular is also the strongest known common genetic risk factor for late-onset Alzheimer's disease, though carrying it doesn't guarantee developing the disease, and many people with Alzheimer's don't carry E4 at all. Because of its link to Alzheimer's risk, some people choose to pursue this test only with genetic counseling, given the personal and sometimes emotionally significant nature of the result.

Tests that include ApoE Genotype

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