Description
Clinical Applications
- Supports Healthy Degradation of Food-Derived Histamine*
- Enhances the Presence of Diamine Oxidase in the Digestive Tract*
Directions
Take one (1) tablet no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare professional
Consult your healthcare professional before use if you are pregnant, breastfeeding or considering use for a child. Individuals taking medication should discuss potential interactions with their healthcare professional.
Store sealed in a cool, dry place and keep out of reach of children.
DAO ENZYME Histamine Digest™
Professional-grade diamine oxidase to support healthy histamine balance and reduce intolerance symptoms.*
Why Histamine Balance Matters
Histamine is a potent signaling molecule involved in inflammation, gastric acid secretion, vascular permeability, and smooth-muscle contraction. Excess dietary histamine—especially from fermented foods, aged cheeses, processed meats, and alcohol—can overwhelm your body’s capacity to degrade it, leading to headaches, flushing, digestive discomfort, rapid heartbeat, and more.* In healthy individuals, the enzyme diamine oxidase (DAO) in the small intestine breaks down ingested histamine; insufficient DAO activity may result in histamine intolerance, which affects at least 1% of the population and is often underdiagnosed.*
Targeted Enzyme Support
DAO Enzyme delivers 20,000 HDU of multi-patented, gastro-resistant diamine oxidase per mini-tablet—precisely where you need it in the small intestine.*
- Optimized Histamine Degradation: Supplies exogenous DAO to convert dietary histamine into inactive imidazole acetaldehyde before absorption.*
- Headache & Migraine Relief: In a double-blind, randomized trial of migraine sufferers with DAO deficiency (N=100), 20,000 HDU per dose significantly shortened attack duration versus placebo.*
- Digestive Comfort: In individuals with functional abdominal complaints (N=28), DAO supplementation before meals for 4 weeks markedly reduced GI, cardiovascular, respiratory, and skin symptoms; symptoms returned when supplementation ceased.*
- Transient Activity: Enzyme peaks in feces by day 3 of daily use and clears within days after stopping—no permanent alteration of gut flora.*
Usage & Safety
Take one mini-tablet before each meal, or as directed by your healthcare practitioner, to maintain a steady histamine threshold.* DAO Enzyme contains no dairy, lactose, or common allergens. Not intended for individuals with diagnosed immune-related food allergies (e.g., peanuts, shellfish, etc.).*
*Based on peer-reviewed clinical and preclinical data.
Formulated To Exclude
Wheat, gluten, corn, yeast, soy, dairy products, fish, shellfish, peanuts, tree nut
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Quality Standards
All Hormunity LLC Formulas Meet or Exceed cGMP Quality Standards
