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DAO Enzyme

$66.99

Histamine Digest

DAO Enzyme Histamine Digest™ provides a concentrated source of diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This formula delivers the clinically researched dose of DAO in an easy-to-swallow, gastro-resistant mini-tablet, which is essential for releasing DAO in the small intestine, where it breaks down food-derived histamine. DAO ENZYME does not manage or address antibody-related or IgE-related food allergies.*

DAO Enzyme Histamine Digest™ provides a concentrated source of diamine oxidase (DAO)—the main enzyme responsible for the degradation of ingested histamine. This formula delivers the clinically researched dose of DAO in an easy-to-swallow, gastro-resistant mini-tablet, which is essential for releasing DAO in the small intestine, where it breaks down food-derived histamine. DAO ENZYME does not manage or address antibody-related or IgE-related food allergies.*

  • Form: Tablets
  • Brand: Hormunity
SKU: HMDAENHD-60
  • Fish Free
  • Gluten Free
  • Non-GMO
  • Soy Free
  • Yeast Free
  • cGMP Certified
  • Made in USA
  • No Preservatives
  • No Artificial Flavors
  • No Artificial Sweeteners

Supplement Facts

Serving Size: 1 tablet Servings Per Container: 60

Amount Per Serving % Daily Value
Pig Kidney Extract (providing 20,000 HDU diamine oxidase (DAO)) 4.2 mg **

Other Ingredients: Microcrystalline cellulose, hydroxypropyl cellulose, coating (ethylcellulose, sodium alginate, hydroxypropyl methylcellulose, medium-chain triglycerides, stearic acid, oleic acid, and microcrystalline cellulose), sodium starch glycolate, and magnesium stearate.

** Daily Value not established.

 

Clinical Applications

  • Supports Healthy Degradation of Food-Derived Histamine*
  • Enhances the Presence of Diamine Oxidase in the Digestive Tract*

 

Directions

Take one (1) tablet no more than 15 minutes before the consumption of histamine-rich foods, or take as directed by your healthcare professional.

Consult your healthcare professional before use if you are pregnant, breastfeeding or considering use for a child. Individuals taking medication should discuss potential interactions with their healthcare professional. Store sealed in a cool, dry place and keep out of reach of children.

 

How It Works

Histamine is a potent signaling molecule involved in inflammation, gastric acid secretion, vascular permeability, and smooth-muscle contraction. Excess dietary histamine—especially from fermented foods, aged cheeses, processed meats, and alcohol—can overwhelm your body’s capacity to degrade it, leading to headaches, flushing, digestive discomfort, rapid heartbeat, and more.* In healthy individuals, the enzyme diamine oxidase (DAO) in the small intestine breaks down ingested histamine; insufficient DAO activity may result in histamine intolerance, which affects at least 1% of the population and is often underdiagnosed.*  

Key Benefits

DAO Enzyme delivers 20,000 HDU of multi-patented, gastro-resistant diamine oxidase per mini-tablet—precisely where you need it in the small intestine.*

  • Optimized Histamine Degradation: Supplies exogenous DAO to convert dietary histamine into inactive imidazole acetaldehyde before absorption.*
  • Headache & Migraine Relief: In a double-blind, randomized trial of migraine sufferers with DAO deficiency (N=100), 20,000 HDU per dose significantly shortened attack duration versus placebo.*
  • Digestive Comfort: In individuals with functional abdominal complaints (N=28), DAO supplementation before meals for 4 weeks markedly reduced GI, cardiovascular, respiratory, and skin symptoms; symptoms returned when supplementation ceased.*
  • Transient Activity: Enzyme peaks in feces by day 3 of daily use and clears within days after stopping—no permanent alteration of gut flora.*

 

Formulated To Exclude

Wheat, gluten, corn, yeast, soy, dairy products, fish, shellfish, peanuts, tree nut

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Quality Standards

All Hormunity LLC Formulas Meet or Exceed cGMP Quality Standards

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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